口服抗凝治疗背景下急性缺血性脑卒中患者机械取栓的研究

V. Yarosh, V. V. Babenko, O. Svyrydiuk, O. Zharinov, O. Yepanchintseva, B. Todurov
{"title":"口服抗凝治疗背景下急性缺血性脑卒中患者机械取栓的研究","authors":"V. Yarosh, V. V. Babenko, O. Svyrydiuk, O. Zharinov, O. Yepanchintseva, B. Todurov","doi":"10.31928/2305-3127-2021.1.3640","DOIUrl":null,"url":null,"abstract":"Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic strategy in case of inefficacy or contraindications to thrombolytic therapy. The article presents a clinical case of the 75-year old female patient with acute cardioembolic stroke on background of heart failure and atrial fibrillation. Long-term background usage of the direct oral anticoagulant due to atrial fibrillation is a limitation to use thrombolytic therapy, therefore mechanical thrombextraction was performed. The case presents possibilities of the successful interventional treatment of acute cardioembolic ischemic stroke. An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown. Key words: ischemic stroke, anticoagulants, mechanical trombextraction.","PeriodicalId":9540,"journal":{"name":"Cardiac Surgery and Interventional Cardiology","volume":"45 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy\",\"authors\":\"V. Yarosh, V. V. Babenko, O. Svyrydiuk, O. Zharinov, O. Yepanchintseva, B. Todurov\",\"doi\":\"10.31928/2305-3127-2021.1.3640\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic strategy in case of inefficacy or contraindications to thrombolytic therapy. The article presents a clinical case of the 75-year old female patient with acute cardioembolic stroke on background of heart failure and atrial fibrillation. Long-term background usage of the direct oral anticoagulant due to atrial fibrillation is a limitation to use thrombolytic therapy, therefore mechanical thrombextraction was performed. The case presents possibilities of the successful interventional treatment of acute cardioembolic ischemic stroke. An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown. Key words: ischemic stroke, anticoagulants, mechanical trombextraction.\",\"PeriodicalId\":9540,\"journal\":{\"name\":\"Cardiac Surgery and Interventional Cardiology\",\"volume\":\"45 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cardiac Surgery and Interventional Cardiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31928/2305-3127-2021.1.3640\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiac Surgery and Interventional Cardiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31928/2305-3127-2021.1.3640","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

溶栓治疗是急性缺血性卒中患者发病后3-4.5小时内的优先治疗策略,但在背景抗凝治疗的情况下有明显的局限性。机械取栓被认为是在溶栓治疗无效或有禁忌症的情况下的一种替代治疗策略。本文报告一例75岁女性急性心栓塞性脑卒中患者,以心力衰竭和心房颤动为背景。由于房颤的直接口服抗凝药物的长期使用限制了使用溶栓治疗,因此进行了机械取栓。该病例提出了成功介入治疗急性心栓塞性缺血性中风的可能性。一个可能的药物-药物相互作用的例子可能导致抗凝治疗的有效性降低。关键词:缺血性卒中,抗凝血剂,机械提取。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy
Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic strategy in case of inefficacy or contraindications to thrombolytic therapy. The article presents a clinical case of the 75-year old female patient with acute cardioembolic stroke on background of heart failure and atrial fibrillation. Long-term background usage of the direct oral anticoagulant due to atrial fibrillation is a limitation to use thrombolytic therapy, therefore mechanical thrombextraction was performed. The case presents possibilities of the successful interventional treatment of acute cardioembolic ischemic stroke. An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown. Key words: ischemic stroke, anticoagulants, mechanical trombextraction.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信