{"title":"自身免疫性疾病是中毒性表皮坏死松解的晚期并发症1例","authors":"I. Couissi","doi":"10.46889/jdr.2023.4207","DOIUrl":null,"url":null,"abstract":"Background: Toxic Epidermal Necrolysis (TEN) is a serious adverse drug reaction causing a potentially fatal mucocutaneous bullous rash and epithelial detachment.\n\nIt is increasingly recognized that survivors may develop late sequelae, some of which may be associated with significant morbidity.\n\nFew studies have mentioned autoimmune diseases as late complications of TEN.\n\nCase report: We report the case of a patient hospitalized for TEN who developed long-term Hashimoto’s thyroiditis and Sjögren’s syndrome.\n\nConclusion: Toxic epidermal necrolysis has a major impact on long-term quality of life. A prolonged multidisciplinary follow-up including a social follow-up is necessary.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"56 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Autoimmune Diseases a Late Complication of Toxic Epidermal Necrolysis: A Case Report\",\"authors\":\"I. Couissi\",\"doi\":\"10.46889/jdr.2023.4207\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Toxic Epidermal Necrolysis (TEN) is a serious adverse drug reaction causing a potentially fatal mucocutaneous bullous rash and epithelial detachment.\\n\\nIt is increasingly recognized that survivors may develop late sequelae, some of which may be associated with significant morbidity.\\n\\nFew studies have mentioned autoimmune diseases as late complications of TEN.\\n\\nCase report: We report the case of a patient hospitalized for TEN who developed long-term Hashimoto’s thyroiditis and Sjögren’s syndrome.\\n\\nConclusion: Toxic epidermal necrolysis has a major impact on long-term quality of life. A prolonged multidisciplinary follow-up including a social follow-up is necessary.\",\"PeriodicalId\":15448,\"journal\":{\"name\":\"Journal of clinical & experimental dermatology research\",\"volume\":\"56 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of clinical & experimental dermatology research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46889/jdr.2023.4207\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical & experimental dermatology research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46889/jdr.2023.4207","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Autoimmune Diseases a Late Complication of Toxic Epidermal Necrolysis: A Case Report
Background: Toxic Epidermal Necrolysis (TEN) is a serious adverse drug reaction causing a potentially fatal mucocutaneous bullous rash and epithelial detachment.
It is increasingly recognized that survivors may develop late sequelae, some of which may be associated with significant morbidity.
Few studies have mentioned autoimmune diseases as late complications of TEN.
Case report: We report the case of a patient hospitalized for TEN who developed long-term Hashimoto’s thyroiditis and Sjögren’s syndrome.
Conclusion: Toxic epidermal necrolysis has a major impact on long-term quality of life. A prolonged multidisciplinary follow-up including a social follow-up is necessary.