{"title":"药理学认知增强:当前科学证据下的生物伦理意义","authors":"Mijail Alejandro Tapia Moreno","doi":"10.1016/j.bioet.2017.05.001","DOIUrl":null,"url":null,"abstract":"<div><p>The use of cognition-enhancing drugs is a topic that currently requires special attention, particularly given the growing patient demand for their prescription. It is essential to examine the ethical aspects inherent to the use of these drugs, especially when they are not an innocuous intervention.</p><p>The effectiveness of these cognition-enhancing drugs lacks the scientific evidence that supports the benefits attributed to them, such as more focus or better memory, as the results in studies show little consistency covering a spectrum from deleterious effects to beneficial effects in certain tasks.</p><p>Considering this background, it is obvious that an assessment is required on how ethical it is to prescribe or recommend them. This assessment can be made based on bioethical principles of non-maleficence, beneficence, autonomy, and justice. Non-maleficence is a concern when reviewing potential adverse effects. Beneficence is unclear, particularly when it is doubtful that the benefits shown in some studies translate into improved performance in the real world. Although the current effectiveness of cognition-enhancing drugs suggests that they do not pose a problem to the justice principle, this should not be an aspect to be dismissed considering that this may change with the development of more effective cognition-enhancing drugs.</p></div>","PeriodicalId":100174,"journal":{"name":"Bioethics Update","volume":"4 2","pages":"Pages 140-153"},"PeriodicalIF":0.0000,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bioet.2017.05.001","citationCount":"2","resultStr":"{\"title\":\"Mejoramiento cognitivo farmacológico: implicaciones bioéticas a la luz de la evidencia científica actual\",\"authors\":\"Mijail Alejandro Tapia Moreno\",\"doi\":\"10.1016/j.bioet.2017.05.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The use of cognition-enhancing drugs is a topic that currently requires special attention, particularly given the growing patient demand for their prescription. It is essential to examine the ethical aspects inherent to the use of these drugs, especially when they are not an innocuous intervention.</p><p>The effectiveness of these cognition-enhancing drugs lacks the scientific evidence that supports the benefits attributed to them, such as more focus or better memory, as the results in studies show little consistency covering a spectrum from deleterious effects to beneficial effects in certain tasks.</p><p>Considering this background, it is obvious that an assessment is required on how ethical it is to prescribe or recommend them. This assessment can be made based on bioethical principles of non-maleficence, beneficence, autonomy, and justice. Non-maleficence is a concern when reviewing potential adverse effects. Beneficence is unclear, particularly when it is doubtful that the benefits shown in some studies translate into improved performance in the real world. Although the current effectiveness of cognition-enhancing drugs suggests that they do not pose a problem to the justice principle, this should not be an aspect to be dismissed considering that this may change with the development of more effective cognition-enhancing drugs.</p></div>\",\"PeriodicalId\":100174,\"journal\":{\"name\":\"Bioethics Update\",\"volume\":\"4 2\",\"pages\":\"Pages 140-153\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.bioet.2017.05.001\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioethics Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2395938X17300244\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioethics Update","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2395938X17300244","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mejoramiento cognitivo farmacológico: implicaciones bioéticas a la luz de la evidencia científica actual
The use of cognition-enhancing drugs is a topic that currently requires special attention, particularly given the growing patient demand for their prescription. It is essential to examine the ethical aspects inherent to the use of these drugs, especially when they are not an innocuous intervention.
The effectiveness of these cognition-enhancing drugs lacks the scientific evidence that supports the benefits attributed to them, such as more focus or better memory, as the results in studies show little consistency covering a spectrum from deleterious effects to beneficial effects in certain tasks.
Considering this background, it is obvious that an assessment is required on how ethical it is to prescribe or recommend them. This assessment can be made based on bioethical principles of non-maleficence, beneficence, autonomy, and justice. Non-maleficence is a concern when reviewing potential adverse effects. Beneficence is unclear, particularly when it is doubtful that the benefits shown in some studies translate into improved performance in the real world. Although the current effectiveness of cognition-enhancing drugs suggests that they do not pose a problem to the justice principle, this should not be an aspect to be dismissed considering that this may change with the development of more effective cognition-enhancing drugs.