Risk of heart rhythm disorders in patients with chronic obstructive pulmonary disease, combined with ischemic heart disease during computer spirography

The aim — to evaluate the safety of spirography with bronchodilation test in patients with a combination of stable ischemic heart disease (IHD) and chronic obstructive pulmonary disease (COPD).Materials and methods. 148 patients were examined including 53 patients with a combination of stable IHD and COPD, 53 IHD patients without concomitant COPD and 42 patients with COPD. Patients underwent general clinical examination, monitoring of an electrocardiogram, echocardiography, spirography.Results and discussion. An increase in the number of extrasystoles within 1 hour after performing spirography was noted, the greatest increase in the number of supraventricular extrasystoles (SVE) was observed in patients with combined pathology — on average (12.6 ± 6.8, p = 0.23). The number of ventricular extrasystoles (VE) within 1 hour after spirography in patients with combined pathology increased by (27.8 ± 12.6, p = 0.0064), whereas in patients with IHD — by (3.4 ± 2.2, p = 0.19), in patients with COPD — by (15.7 ± 12.5, p = 0.076). An increase in the number or occurrence of polytropic VE was reported in 4 (7.5 %) persons with combined pathology, in 2 (3.8 %) patients with IHD and in 3 (7.1 %) patients with COPD. The occurrence of high‑grade VE during spirography was established in 11 (20.7 %, p = 0.008) patients with a combination of IHD and COPD, in 5 (9.4 %, p = 0.06) patients with isolated course of IHD and in 3 (7.1 %, p = 0.23) patients with COPD. The predictors of an increase in the number of VE within 1 hour after performing spirography for patients with IHD and COPD were identified.Conclusions. Spirography is associated with the occurrence of rhythm disorders in patients with a combination of IHD and COPD. Prior to spirography, patients with IHD should undergo echocardiography and daily monitoring of the electrocardiogram.