{"title":"克罗恩病的小肠复杂的过程中,在生命的第八个十年的病人","authors":"Štěpán Peterka","doi":"10.48095/ccgh202230","DOIUrl":null,"url":null,"abstract":"Crohn‘s disease (CD) comes within the group of idiopathic bowel diseases (IDP), together with ulcerative colitis (UC). Their common characteristic is that genetically predisposed individuals suffer from chronic digestive tract inflammation. In spite of almost 90 years of experience, CD remains an incurable disease. The clinical manifestation of the disease displays great heterogeneity. A discrepancy between the clinical picture and morphological finding in the digestive tract is one of the typical features of CD. Basic treatment consists of pharmacotherapy – conventional and/or biological – and surgery where needed. The aim is to achieve and maintain deep remission, limit the number of large-scale surgical interventions, and normalise the patients’ quality of life. The case history presents a female patient suffering from CD with extensive penetrating damage of the small intestine diagnosed in the eighth decade of her life. The patient’s case illustrates the difficulty of treating elderly patients, especially in the case of a severe form of Crohn’s disease. Keywords Crohn’s disease, surgical treatment, penetrující forma, exkluzivní enterální výživa","PeriodicalId":38577,"journal":{"name":"Gastroenterologie a Hepatologie","volume":"154 1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Complicated course of Crohn’s disease of the small intestine in the patient in the eighth decade of life\",\"authors\":\"Štěpán Peterka\",\"doi\":\"10.48095/ccgh202230\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Crohn‘s disease (CD) comes within the group of idiopathic bowel diseases (IDP), together with ulcerative colitis (UC). Their common characteristic is that genetically predisposed individuals suffer from chronic digestive tract inflammation. In spite of almost 90 years of experience, CD remains an incurable disease. The clinical manifestation of the disease displays great heterogeneity. A discrepancy between the clinical picture and morphological finding in the digestive tract is one of the typical features of CD. Basic treatment consists of pharmacotherapy – conventional and/or biological – and surgery where needed. The aim is to achieve and maintain deep remission, limit the number of large-scale surgical interventions, and normalise the patients’ quality of life. The case history presents a female patient suffering from CD with extensive penetrating damage of the small intestine diagnosed in the eighth decade of her life. The patient’s case illustrates the difficulty of treating elderly patients, especially in the case of a severe form of Crohn’s disease. Keywords Crohn’s disease, surgical treatment, penetrující forma, exkluzivní enterální výživa\",\"PeriodicalId\":38577,\"journal\":{\"name\":\"Gastroenterologie a Hepatologie\",\"volume\":\"154 1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-02-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gastroenterologie a Hepatologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.48095/ccgh202230\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gastroenterologie a Hepatologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.48095/ccgh202230","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
克罗恩病(CD)与溃疡性结肠炎(UC)一起属于特发性肠病(IDP)。他们的共同特点是遗传易感个体患有慢性消化道炎症。尽管有近90年的经验,乳糜泻仍然是一种不治之症。本病的临床表现具有很大的异质性。消化道的临床表现与形态学表现之间的差异是CD的典型特征之一。基本治疗包括常规和/或生物药物治疗和必要的手术。目的是实现和维持深度缓解,限制大规模手术干预的数量,并使患者的生活质量正常化。本病例是一位女性乳糜泻患者,在她八十岁时被诊断为广泛的小肠穿透性损伤。病人的情况说明了治疗老年病人的困难,特别是在克罗恩病严重的情况下。关键词克罗恩病,手术治疗,penetrující forma, exkluzivní enterální výživa
Complicated course of Crohn’s disease of the small intestine in the patient in the eighth decade of life
Crohn‘s disease (CD) comes within the group of idiopathic bowel diseases (IDP), together with ulcerative colitis (UC). Their common characteristic is that genetically predisposed individuals suffer from chronic digestive tract inflammation. In spite of almost 90 years of experience, CD remains an incurable disease. The clinical manifestation of the disease displays great heterogeneity. A discrepancy between the clinical picture and morphological finding in the digestive tract is one of the typical features of CD. Basic treatment consists of pharmacotherapy – conventional and/or biological – and surgery where needed. The aim is to achieve and maintain deep remission, limit the number of large-scale surgical interventions, and normalise the patients’ quality of life. The case history presents a female patient suffering from CD with extensive penetrating damage of the small intestine diagnosed in the eighth decade of her life. The patient’s case illustrates the difficulty of treating elderly patients, especially in the case of a severe form of Crohn’s disease. Keywords Crohn’s disease, surgical treatment, penetrující forma, exkluzivní enterální výživa