经腹平面(tap)阻滞用于全麻腹式子宫切除术患者术中及术后镇痛的疗效——一项随机对照研究

Kaushal Kumar, G. Bhandari, K. Shahi
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引用次数: 0

摘要

背景:探讨经腹阻滞对全麻下腹式子宫切除术患者术中及术后镇痛的影响。方法:对80例40 ~ 60岁全麻腹式全子宫切除术患者进行前瞻性、双盲、随机、临床研究。患者随机分为2组;N组(N =40):用生理盐水30 ml阻断TAP;B组(n= 40):用0.25%布比卡因30 ml阻断TAP。所有患者均予全身麻醉后行腹横平面阻滞(TAP)。记录术后VAS评分、术中血流动力学变化(HR、SBP、DBP、MAP)等参数。术后给予双氯芬酸1.5 mg/kg。如果VAS≥4分,给予曲马多2mg/kg静脉注射作为抢救性镇痛。记录双氯芬酸和曲马多术后24小时的总剂量。结果:B组首次请求镇痛时间(134.67±16.23 min)明显高于N组(42.85±18.13 min) (P值<0.05)。B组术后24 h VAS评分(2.77±9.73)低于N组(5.6±1.42)(P值<0.05)。B组术后24 h抢救镇痛药用量(105.75±71.24 mg)低于N组(218±40.01 mg) (P值<0.05)。结论:TAP阻滞具有明显的术后24小时镇痛效果和良好的血流动力学稳定性,是腹式全子宫切除术术中、术后镇痛的安全方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of transversus abdominis plane (tap) block for intraoperative and postoperative analgesia in patients undergoing abdominal hysterectomy under general anaesthesia- a randomised controlled study
Background: To evaluate the effect of transversus abdominis block for intra and post-operative analgesia in patients undergoing abdominal hysterectomy under general anaesthesia.Methods: Prospective, double-blind, randomized, clinical study on 80 patients of age 40-60 years undergoing total abdominal hysterectomy under general anaesthesia. Patients were randomly divided into 2 equal groups; Group N (n=40): TAP block with 30 ml of normal saline; Group B (n= 40): TAP block with 30 ml of 0.25% bupivacaine. All patients were given general anaesthesia followed by transversus abdominis plane block (TAP). All parameters like postoperative VAS Score, intraoperative haemodynamic changes (HR, SBP, DBP, MAP) were recorded. In the postoperative period diclofenac 1.5 mg/kg was given. If VAS ≥ 4 inj tramadol 2mg/kg i.v. was given as rescue analgesia. Total dose of diclofenac and tramadol in 24 hr post operative period was recorded.Result: The time for first analgesic request was increased in Group B 134.67±16.23 min  as compared to Group N 42.85±18.13 min  (P value  <0.05). Maximum VAS score up to 24 hrs postoperative was lower in the Group B (2.77 ± 9.73) as compared to group N (5.6±1.42) (P value <0.05). The rescue analgesic consumption within 24 hours post operatively was lower in Group B (105.75±71.24 mg) compared to Group N (218±40.01 mg) (P value <0.05).Conclusion: TAP block provide significant postoperative analgesia in first 24 hour and excellent hemodynamic stability being a safe modality for intra and post operative analgesia for total abdominal hysterectomy.
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