新型冠状病毒(COVID-19)经口-粪便传播及其预防与管理的前瞻性研究

A. Abdullah, S. Faisal, Hasnain Jan, R. Zainab, A. Khan, A. Rahman, Baseerat Bibi, Hania Ishaq
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引用次数: 5

摘要

新型冠状病毒疫情于2019年12月在中国武汉爆发。这是世界卫生组织宣布的第六次突发公共卫生事件,并被命名为COVID-19。SARS-CoV-2是一种非分节性阳性rna病毒,属于尼多科冠状病毒科,主要在人类和其他哺乳动物中传播。人与人之间,空气传播和表面传播是常见的,病毒通过鼻、口、眼、食物、水和粪便进入宿主。一名感染者可将病毒传染给2.2名健康人。美国的一名患者出现了胃肠道症状呕吐、恶心和便稀。后来,根据粪便和呼吸道样本中的病毒检测,患者宣布SARS-CoV-2阳性。感染和康复患者出现腹泻、恶心、呕吐、腹部不适等胃肠道症状,粪便中检出SARS-CoV-2,提示存在潜在的口粪传播途径,可能存在新冠病毒传播的潜在风险。肠胃胀气是由肠道内的气噬或细菌发酵产生的气体,经食道或肛门排出体外。它由氢、氧、氮、二氧化碳和甲烷组成,它们的百分比组成为99%。先前的研究表明细菌可以通过光屁股放屁传播。胃肠道表现和可能的口粪传播,胀气可能是COVID-19传播的风险。个人卫生必须适应预防疾病的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Perspective Study on Oral-fecal Transmission of COVID-19, its Prevention and Management
The novel coronavirus outbreak arose in Wuhan, China in Dec, 2019. It is declared the 6th public health emergency by the WHO and named as COVID-19. SARS-CoV-2 is non-segmented positive sense ssRNA virus, belongs to the Coronaviridae under the Nidovirales and spread largely in human being and other mammals. Person to person, airborne and surface transmission is common, the virus gets entered to host through nose, mouth, eyes, food, water and feces. An infected patient can transmit the virus to 2.2 healthy individuals.  A patient in the US showed gastrointestinal symptoms vomiting, nausea and pass loose stools. Later the patient declared positive for SARS-CoV-2 based on viral detection in stools and respiratory samples. The gastrointestinal symptoms like diarrhea, nausea, vomiting, abdominal discomfort and detection of SARS-CoV-2 in stools of infected and recovered patients indicates potential oral-fecal transmission route, it could be potential risk for the spread of COVID-19. The flatus is gas produced by aerophagia or bacterial fermentation in intestine and expelled out through esophagus or anus. It consists of Hydrogen, Oxygen, Nitrogen, Carbon dioxide and Methane, their percentage composition is 99%. Previous study showed that bacteria can transmit through bare-bottom farting. The gastrointestinal manifestation and possible oral-fecal transmission, the flatulence could be the risk of transmission for COVID-19. Personal hygiene must be adapted to prevent the spread of disease. 
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