Mohammad Rilwanu Rafsanjani, T. Y. Pramana, Arifin
{"title":"无合并症的初发慢性乙型肝炎患者Fischer比值与肝纤维化的相关性","authors":"Mohammad Rilwanu Rafsanjani, T. Y. Pramana, Arifin","doi":"10.24203/ajpnms.v9i6.6786","DOIUrl":null,"url":null,"abstract":"Introduction:\nHepatitis B virus infection is one of the most common health problems in the world. 20% Chronic hepatitis B can can change into liver fibrosis. The liver is the center of the body's Amino Acids metabolism. Amino acid changes can occur due to impaired liver function. Fisher's ratio (BCAA/AAA) has become one of the sign of liver fibrosis. This study wanted to find a relationship between Fischer Ratio values and liver fibrosis in naive chronic hepatitis B patients without comorbidities.\nMethod:\nThe research was conducted from October 2020-May 2021 at DR. Moewardi Hospital, Surakarta, Indonesia. Subjects were naive chronic hepatitis B patients without comorbidities with a minimum age of 30 years. The study used a cross-sectional method. Fischer Ratio values were assessed by spectrophotometry and liver fibrosis was assessed by transient elastography (fibroscan). A correlation test was conducted to determine the relationship between variables.\nResult:\n20 patients were included in the study. The average age of the research subjects was 47 ± 10 years. The average Fisher's ratio value was 2.83 ± 1.16 and the average fibroscan value was 17.31 ± 18.50 kPa. Ratio Fischer had a correlation with liver fibrosis with r= - 0.571 (p=0.004).\nConclusions:\nRatio Fischer has a negative correlation with liver fibrosis in naive chronic hepatitis B patients without comorbidities.\n \n ","PeriodicalId":8530,"journal":{"name":"Asian Journal of Pharmacy, Nursing and Medical Sciences","volume":"47 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Correlation of Fischer’s Ratio with Liver Fibrosis in Naive Chronic Hepatitis B Patients without Comorbidities\",\"authors\":\"Mohammad Rilwanu Rafsanjani, T. Y. Pramana, Arifin\",\"doi\":\"10.24203/ajpnms.v9i6.6786\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction:\\nHepatitis B virus infection is one of the most common health problems in the world. 20% Chronic hepatitis B can can change into liver fibrosis. The liver is the center of the body's Amino Acids metabolism. Amino acid changes can occur due to impaired liver function. Fisher's ratio (BCAA/AAA) has become one of the sign of liver fibrosis. This study wanted to find a relationship between Fischer Ratio values and liver fibrosis in naive chronic hepatitis B patients without comorbidities.\\nMethod:\\nThe research was conducted from October 2020-May 2021 at DR. Moewardi Hospital, Surakarta, Indonesia. Subjects were naive chronic hepatitis B patients without comorbidities with a minimum age of 30 years. The study used a cross-sectional method. Fischer Ratio values were assessed by spectrophotometry and liver fibrosis was assessed by transient elastography (fibroscan). A correlation test was conducted to determine the relationship between variables.\\nResult:\\n20 patients were included in the study. The average age of the research subjects was 47 ± 10 years. The average Fisher's ratio value was 2.83 ± 1.16 and the average fibroscan value was 17.31 ± 18.50 kPa. Ratio Fischer had a correlation with liver fibrosis with r= - 0.571 (p=0.004).\\nConclusions:\\nRatio Fischer has a negative correlation with liver fibrosis in naive chronic hepatitis B patients without comorbidities.\\n \\n \",\"PeriodicalId\":8530,\"journal\":{\"name\":\"Asian Journal of Pharmacy, Nursing and Medical Sciences\",\"volume\":\"47 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Pharmacy, Nursing and Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24203/ajpnms.v9i6.6786\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Pharmacy, Nursing and Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24203/ajpnms.v9i6.6786","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Correlation of Fischer’s Ratio with Liver Fibrosis in Naive Chronic Hepatitis B Patients without Comorbidities
Introduction:
Hepatitis B virus infection is one of the most common health problems in the world. 20% Chronic hepatitis B can can change into liver fibrosis. The liver is the center of the body's Amino Acids metabolism. Amino acid changes can occur due to impaired liver function. Fisher's ratio (BCAA/AAA) has become one of the sign of liver fibrosis. This study wanted to find a relationship between Fischer Ratio values and liver fibrosis in naive chronic hepatitis B patients without comorbidities.
Method:
The research was conducted from October 2020-May 2021 at DR. Moewardi Hospital, Surakarta, Indonesia. Subjects were naive chronic hepatitis B patients without comorbidities with a minimum age of 30 years. The study used a cross-sectional method. Fischer Ratio values were assessed by spectrophotometry and liver fibrosis was assessed by transient elastography (fibroscan). A correlation test was conducted to determine the relationship between variables.
Result:
20 patients were included in the study. The average age of the research subjects was 47 ± 10 years. The average Fisher's ratio value was 2.83 ± 1.16 and the average fibroscan value was 17.31 ± 18.50 kPa. Ratio Fischer had a correlation with liver fibrosis with r= - 0.571 (p=0.004).
Conclusions:
Ratio Fischer has a negative correlation with liver fibrosis in naive chronic hepatitis B patients without comorbidities.