一些药用植物对选定细菌的抗菌筛选

Pragya Sapkota, S. Bhattarai, Anup Muni Bajracharya, P. Lakhe, N. Shrestha
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引用次数: 1

摘要

药用植物被用作许多人类疾病的传统疗法。据世界卫生组织称,药用植物将是获得各种药物的最佳来源。与合成药物相反,植物来源的抗菌素没有许多副作用,在治疗许多传染病方面具有巨大的治疗潜力。本研究于2017年10月至2018年1月对部分药用植物对选定病原菌的筛选进行了研究。共筛选了9种不同的药用植物,并对其对10种细菌的抗菌活性进行了评价。其中,对革兰氏阳性菌(枯草芽孢杆菌、金黄色葡萄球菌、耐甲氧西林金黄色葡萄球菌MRSA)有有效抑制作用的有大戟属、印楝属、鸢尾花属、合子属、刺草属、刺叶属等6种药用植物,对枯草芽孢杆菌、大肠杆菌、肺炎克雷伯菌、普通变形杆菌、金黄色葡萄球菌、耐甲氧西林金黄色葡萄球菌MRSA均无有效抑制作用。气源假单胞菌,伤寒沙门氏菌,志贺氏杆菌,耐甲氧西林金黄色葡萄球菌)。大红花对枯草芽孢杆菌和金黄色葡萄球菌的最低杀菌浓度(MBC)为12.5mg/ml,普通蒿对枯草芽孢杆菌和MRSA的最低杀菌浓度(MBC)为12.5mg/ml,金黄色葡萄球菌的最低杀菌浓度为25mg/ml。同样,印楝对金黄色葡萄球菌的MBC为25mg/ml。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antimicrobial Screening of some Medicinal Plants against Selected Bacterial Species
Medicinal plants are used as traditional treatment for numerous human diseases. According to WHO, medicinal plants would be the best source to obtain a variety of drugs. Contrary to the synthetic drugs, antimicrobial of plant origin are not associated with many side effects and have an enormous therapeutic potential to heal many infectious diseases. Present study was carried out on the screening of some medicinal plants against selected pathogenic organisms in the period of October 2017 to January 2018. A total of nine different medicinal plants were screened and evaluated for their antimicrobial activity against 10 bacterial species. Among them, Euphorbia hirta, Azadirachtaindica, Artemisia vulgaris were found to be effective against gram positive bacteria (Bacillus subtilis, Staphylococcus aureus, Methicillin resistant Staphylococcus aureus MRSA), whereas rest six medicinal plants (Aeglemarmelos, Justiciaadhatoda, Ficusreligiosa, Syzygiumcumini, Nyctanthes arbor and Meliaazedarach) were found to be ineffective against all the microorganisms(Bacillus subtilis, Escherichia coli, Klebsiellapneumoniae, Proteus vulgaris, Pseudomonas aerogenosa, Salmonella typhii, Shigelladysentriae, MRSA). The minimum bactericidal concentration (MBC) of Euphorbia hirta against Bacillus subtilis and Staphylococcus aureus was found to be 12.5mg/ml and MBC of Artemisia vulgaris against Bacillus subtilis and MRSA was also found to be 12.5 mg/ml while of Staphylococcus aureus was 25mg/ml. Similarly, the MBC of Azadirachta indica against Staphylococcus aureus was 25mg/ml.
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