{"title":"含喹啉核杂环化合物的抗菌筛选","authors":"S. Baluja, N. Godvani, S. Chanda","doi":"10.18052/WWW.SCIPRESS.COM/ILCPA.76.27","DOIUrl":null,"url":null,"abstract":"In this work, some novel derivatives of Cyanopyridines and Isoxazoles were synthesized using Vilsmeier-Haack reagent and their structures were confirmed by FTIR, 1H NMR and mass spectroscopic methods. The antibacterial activities of these synthesized compounds were studied in DMSO and DMF by agar well diffusion method against some Gram positive and Gram negative bacteria. It is observed that activity depends upon three S: solvent, strain and structure.","PeriodicalId":14453,"journal":{"name":"International Letters of Chemistry, Physics and Astronomy","volume":"9 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Antibacterial Screening of some Heterocyclic Compounds Containing Quinoline Nucleus\",\"authors\":\"S. Baluja, N. Godvani, S. Chanda\",\"doi\":\"10.18052/WWW.SCIPRESS.COM/ILCPA.76.27\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this work, some novel derivatives of Cyanopyridines and Isoxazoles were synthesized using Vilsmeier-Haack reagent and their structures were confirmed by FTIR, 1H NMR and mass spectroscopic methods. The antibacterial activities of these synthesized compounds were studied in DMSO and DMF by agar well diffusion method against some Gram positive and Gram negative bacteria. It is observed that activity depends upon three S: solvent, strain and structure.\",\"PeriodicalId\":14453,\"journal\":{\"name\":\"International Letters of Chemistry, Physics and Astronomy\",\"volume\":\"9 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Letters of Chemistry, Physics and Astronomy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18052/WWW.SCIPRESS.COM/ILCPA.76.27\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Letters of Chemistry, Physics and Astronomy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18052/WWW.SCIPRESS.COM/ILCPA.76.27","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antibacterial Screening of some Heterocyclic Compounds Containing Quinoline Nucleus
In this work, some novel derivatives of Cyanopyridines and Isoxazoles were synthesized using Vilsmeier-Haack reagent and their structures were confirmed by FTIR, 1H NMR and mass spectroscopic methods. The antibacterial activities of these synthesized compounds were studied in DMSO and DMF by agar well diffusion method against some Gram positive and Gram negative bacteria. It is observed that activity depends upon three S: solvent, strain and structure.
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