{"title":"奥美拉唑类药物对褐家鼠血液图像的影响","authors":"S. Jassim, A. M. Hussin","doi":"10.9790/3008-1203045659","DOIUrl":null,"url":null,"abstract":"In the current study the long-term effect of omeprazole was determined by measuring some hematological parameters .Three groups of laboratory rats were taken each group (6) individual, the first groups was the control, second and third were given the drug with a dose of 20 and 40 respectively for three consecutive months. There are significant effects at (p˃0.05) in all parameters which include white and red blood cells counts(WBC and RBC), Hemoglobin concentration(Hb) and the ratio of neutrophils and lymphocytes in both treated groups(the effect is significant for both doses) compared with control, That is, there was a clear effect of omeprazole on the blood picture.","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"98 1","pages":"56-59"},"PeriodicalIF":0.0000,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Effect of Omeprazole Drug on the Blood Picture of Laboratory Rat Rattus Norvegicus\",\"authors\":\"S. Jassim, A. M. Hussin\",\"doi\":\"10.9790/3008-1203045659\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current study the long-term effect of omeprazole was determined by measuring some hematological parameters .Three groups of laboratory rats were taken each group (6) individual, the first groups was the control, second and third were given the drug with a dose of 20 and 40 respectively for three consecutive months. There are significant effects at (p˃0.05) in all parameters which include white and red blood cells counts(WBC and RBC), Hemoglobin concentration(Hb) and the ratio of neutrophils and lymphocytes in both treated groups(the effect is significant for both doses) compared with control, That is, there was a clear effect of omeprazole on the blood picture.\",\"PeriodicalId\":14548,\"journal\":{\"name\":\"IOSR Journal of Pharmacy and Biological Sciences\",\"volume\":\"98 1\",\"pages\":\"56-59\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IOSR Journal of Pharmacy and Biological Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9790/3008-1203045659\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Pharmacy and Biological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/3008-1203045659","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Effect of Omeprazole Drug on the Blood Picture of Laboratory Rat Rattus Norvegicus
In the current study the long-term effect of omeprazole was determined by measuring some hematological parameters .Three groups of laboratory rats were taken each group (6) individual, the first groups was the control, second and third were given the drug with a dose of 20 and 40 respectively for three consecutive months. There are significant effects at (p˃0.05) in all parameters which include white and red blood cells counts(WBC and RBC), Hemoglobin concentration(Hb) and the ratio of neutrophils and lymphocytes in both treated groups(the effect is significant for both doses) compared with control, That is, there was a clear effect of omeprazole on the blood picture.
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