MRI脑成像评估儿童头部创伤

Kathan A Amin, Sharjeel Israr, D. Gopireddy, U. Udayasankar
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引用次数: 0

摘要

T是1岁以上儿童死亡的主要原因,创伤性脑损伤(TBI)是创伤导致死亡和残疾的主要原因,占致死性伤害的70%在美国,每年有3000人死亡,50000人住院,675000人急诊与钝性头部创伤有关2 .脑外伤是全世界,特别是儿童和青年中的一个重大公共卫生和社会经济问题即使在没有任何可识别的初始临床表现的患者中,如果不治疗,它仍然会对神经认知功能和社会心理行为产生破坏性的长期后果。近年来,计算机断层扫描(CT)的使用有所增加,因此可以早期识别TBI。因此,最近的许多研究表明,一生中患癌症的风险与CT检查产生的电离辐射有关。与成年人相比,幼儿一生中患癌症的风险更高。尽管CT仍然是用于儿童头部损伤初步评估的主要成像方式,但更快的磁共振成像(MRI)技术已被证明在识别脑损伤的细微发现方面更为敏感。具体来说,MRI已被用于区分亚急性和慢性脑损伤,以及确定脑病、反应性神经胶质瘤和出血相关的程度。摘要目的:尽管计算机断层扫描(CT)一直是用于儿童头部损伤初步评估的主要成像方式,但较新的磁共振成像(MRI)技术已被证明在识别脑损伤的细微表现方面更为敏感。具体来说,MRI已被用于区分亚急性和慢性脑损伤,并确定脑病、反应性神经胶质瘤和与损伤相关的出血的程度。在这篇文献综述中,我们打算介绍MR在评估儿童头部创伤中的应用和益处的最新信息。方法从Medline和PubMed检索1990年1月至2018年12月的所有同行评议稿件,使用多个关键词进行文献检索。先前的搜索包括儿童头部创伤、儿童TBI、头部创伤成像、MRI评估和儿童头部创伤的长期影响。经过仔细的分析,本文选择了最重要的观点并进行了总结。结果除颅骨骨折外,MRI对绝大多数颅脑损伤的诊断敏感性均高于CT。结论:与CT检查相比,在头部创伤的情况下,MRI提供了一种独特的成像方式,可以提供额外的临床信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MRI Brain Imaging in Assessment of Pediatric Head Trauma
T is the leading cause of death in children over the age of one, and traumatic brain injury (TBI) is the leading cause of death and disability due to trauma, accounting for 70% of fatal injuries.1 In the United States, every year there are 3,000 deaths, 50,000 hospitalizations and 675,000 emergency room (ER) visits related to blunt head trauma.1 TBI is a major public health and socio-economic problem throughout the world, especially among children and young adults.2 Even in patients who do not have any recognizable initial clinical manifestations, it can still have devastating long-term consequences on neurocognitive function and psychosocial behavior, if untreated. The use of computed tomography (CT) has increased in recent years, thus enabling early identification of TBI. Accordingly, many recent studies have shown an association between lifetime risk of developing cancer and ionizing radiation from CT exams. This lifetime risk of cancer is higher in young children when compared to adults.3,4 Though CT has remained the mainstay imaging modality used in the initial evaluation of pediatric head injury, faster magnetic resonance imaging (MRI) techniques have proven to be more sensitive in identifying subtle findings of brain injury. Specifically, MRI has been used in differentiating subacute and chronic brain injury, and identifying the extent of encephalopathy, reactive gliosis, and hemorrhage related ABSTRACT Purpose Though computed tomography (CT) has been the mainstay imaging modality used in the initial evaluation of pediatric head injury, newer magnetic resonance imaging (MRI) techniques have proven to be more sensitive in identifying subtle findings of brain injury. Specifically, MRI has been used in differentiating subacute and chronic brain injury, and identifying the extent of encephalopathy, reactive gliosis, and hemorrhage related to the insult. In this literature review, we intend to present the current information about the use and benefits of MR in evaluating pediatric head trauma. Methods Literature search was done from Medline and PubMed for all peer-reviewed manuscripts from January 1990 and December 2018 using several keywords. The preceding searches included pediatric head trauma, pediatric TBI, imaging in head trauma, MRI in head trauma evaluation, and long-term effects of pediatric head trauma. After careful analysis, the most important points were chosen and summarized in this review. Results MRI has greater sensitivity in the detection of most types of head injuries, in comparison to CT – except skull fractures. Conclusions In the setting of head trauma, MRI provides an imaging modality with a unique ability to provide additional clinical information compared to CT examination.
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