Khaled Gaballa, Omar Hamdy, B. Refky, M. Abdelkhalek
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引用次数: 0
摘要
背景:手术一直被认为是子宫内膜癌治疗的基石,尤其是在其早期阶段。微创手术治疗子宫内膜癌在世界范围内已被广泛采用。在本研究中,我们讨论了I型子宫内膜癌患者在我们中心接受腹腔镜子宫切除术的结果。结果:患者分为两组:开放手术组59例,腹腔镜组60例。两组在流行病学和临床病理参数方面无显著差异。FIGO (International Federation of Gynecology and Obstetrics)阶段两组比较无统计学差异。腹腔镜组手术时间明显长于开放组(p < 0.0001)。两组在手术类型和出血量方面无明显差异。两组术中并发症发生率几乎相同。两组患者淋巴结清扫数比较,差异无统计学意义。结论:本研究结果支持腹腔镜在早期I型子宫内膜癌中的应用,且不影响无病和总生存期的肿瘤预后。我们鼓励进一步的前瞻性多中心随机试验来巩固这些结果。
Laparoscopic versus open hysterectomy in type I endometrial cancer – a tertiary referral center experience
Background: Surgery has been considered the cornerstone in the management of endometrial cancer, especially in its early stages. The use of minimally invasive surgeries in patients with endometrial cancers has been widely adopted worldwide. In this study, we discuss the outcomes of type I endometrial cancer patients who underwent laparoscopic hysterectomy at our center. Results: The patients were categorized into two groups: open surgery group (59 patients) and laparoscopy group (60 patients). There was no significant difference between both groups as regards the epidemiologic and clinicopathologic parameters. There was no statistical difference between the two groups in the FIGO stage (International Federation of Gynecology and Obstetrics). Operative time was significantly longer in the laparoscopy group compared to the open surgery group (p < 0.0001). No significant difference was found between both groups as regards the type of operation and blood loss. The rate of intraoperative complications was nearly similar in both groups. There was no significant statistical difference between the numbers of lymph node yield in both groups. Conclusion: The results in this study support the use of laparoscopy in early stage type I endometrial cancers without compromising the oncological outcomes regarding the disease-free and overall survival. We encourage further prospective multicenter randomized trials to consolidate these results.