心脏肿瘤致冠状动脉栓塞的临床表现

R. M. Vitovsky, V. V. Isaіenko, O.V. Kupchinsky, I.V. Martyschenko, M. M. Serdyuk
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摘要

目的:介绍两例以左心房肿瘤碎片为栓塞底物的冠状动脉栓塞的临床表现和病程特点。材料和方法。本文讨论两例冠状动脉肿瘤碎片栓塞。本例肿瘤位于左心。特别有趣的是,栓塞的临床表现差异很大,从需要血管内干预的剧烈疼痛到持续数小时的轻微不适,无需住院治疗。结果。值得注意的是,在这两例中,心脏肿瘤病变是在疾病的主要表现(即冠状动脉栓塞)出现几个月后才被发现的。超声心动图检查使正确诊断成为可能。其中一例为冠状动脉支架植入术后6个月的常规检查。另一例超声心动图的原因是心电图显示左心室后壁坏死改变。在这两个病例中,超声心动图数据提示立即手术治疗肿瘤。手术获得的肿瘤样本的结构证实了肿瘤碎片导致冠状动脉栓塞的可能性。结论。栓塞并发症可能是心脏肿瘤的首要表现。心脏肿瘤的碎裂可能导致大脑和冠状动脉的损伤。栓塞并发症可发生在年轻患者中。心脏肿瘤冠状动脉栓塞具有多种临床表现。关键词:黏液瘤,心脏肿瘤,栓塞并发症,冠状动脉,冠状动脉造影。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical manifestations of coronary artery embolism due to heart tumors
The aim – to present the features of the clinical manifestations and course of two cases of embolism of the coronary arteries, in which fragments of left atrial (LA) tumors served as the embolic substrate. Materials and methods. This article discusses two cases of embolism with tumor fragments of the coronary arteries. In this case, the neoplasms were located in the left heart. Of particular interest is the fact that the clinical manifestations of embolism varied significantly, from severe pain requiring endovascular intervention, to minor discomfort lasting for several hours, without necessity of the inpatient treatment. Results. It should be noted that in both cases, a tumor lesion of the heart was detected several months after primary manifestation of the disease, namely, embolism of the coronary arteries. Echocardiography study made possible to get a correct diagnosis. In one case it was a routine examination 6 months after stenting of the coronary artery. The reason to perform echocardiography in another case was the result of electrocardiography, showing necrotic changes of the left ventricular posterior wall. In both cases, echocardiographic data prompted immediate surgery of the neoplasms. The structure of neoplasm samples obtained as a result of the surgery confirmed the possibility of coronary artery embolism with tumor fragments. Conclusions. Embolic complications may be a first manifestation of cardiac tumor. Fragmentation of the heart neoplasms may lead to damage of the cerebral and coronary arteries. Embolic complications can occur in young patients. Coronary artery embolism in cardiac tumors is associated with diverse clinical manifestations. Key words: myxoma, heart tumors, embolic complications, coronary arteries, coronary angiography.
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