局部宫内麻醉

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引用次数: 0

摘要

第一个被发现的局部麻醉剂是可卡因,一种在安第斯山脉生长的红杉(Erythroxylon cocaa)灌木叶子上的大量生物碱(0.6 - 1.8%)。大量的药物被口服和每年服用。咀嚼时,植物灰释放出植物生物碱,并通过口腔粘膜吸收。1880年,尼曼注意到咀嚼这种物质时舌头会麻木,没有感觉。众所周知,利多卡因是通过粘膜吸收的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Local Intrauterine Anesthesia
The first local anesthetic to be discovered was cocaine an alkaloid in large amount (0.6 to 1.8%) on the leaves of Erythroxylon coca a shrub growing in the Andes Mountains. Vast quantities were consumed orally and annually. The plant ash when chewed releases the plant alkaloid and absorbed across the mouth mucous membrane. In 1880 Niemann noted that the tongue was numb with no sensation upon chewing this substance. It is well known that Lidocaine was absorbed across the mucous membrane.
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