{"title":"局部宫内麻醉","authors":"","doi":"10.33140/jgrm.03.06.01","DOIUrl":null,"url":null,"abstract":"The first local anesthetic to be discovered was cocaine an alkaloid\nin large amount (0.6 to 1.8%) on the leaves of Erythroxylon coca\na shrub growing in the Andes Mountains. Vast quantities were\nconsumed orally and annually. The plant ash when chewed releases\nthe plant alkaloid and absorbed across the mouth mucous membrane.\nIn 1880 Niemann noted that the tongue was numb with no sensation\nupon chewing this substance. It is well known that Lidocaine was\nabsorbed across the mucous membrane.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":"32 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Local Intrauterine Anesthesia\",\"authors\":\"\",\"doi\":\"10.33140/jgrm.03.06.01\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The first local anesthetic to be discovered was cocaine an alkaloid\\nin large amount (0.6 to 1.8%) on the leaves of Erythroxylon coca\\na shrub growing in the Andes Mountains. Vast quantities were\\nconsumed orally and annually. The plant ash when chewed releases\\nthe plant alkaloid and absorbed across the mouth mucous membrane.\\nIn 1880 Niemann noted that the tongue was numb with no sensation\\nupon chewing this substance. It is well known that Lidocaine was\\nabsorbed across the mucous membrane.\",\"PeriodicalId\":93778,\"journal\":{\"name\":\"Journal of gynecology, clinical obstetrics and reproductive medicine\",\"volume\":\"32 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of gynecology, clinical obstetrics and reproductive medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33140/jgrm.03.06.01\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of gynecology, clinical obstetrics and reproductive medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33140/jgrm.03.06.01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The first local anesthetic to be discovered was cocaine an alkaloid
in large amount (0.6 to 1.8%) on the leaves of Erythroxylon coca
a shrub growing in the Andes Mountains. Vast quantities were
consumed orally and annually. The plant ash when chewed releases
the plant alkaloid and absorbed across the mouth mucous membrane.
In 1880 Niemann noted that the tongue was numb with no sensation
upon chewing this substance. It is well known that Lidocaine was
absorbed across the mucous membrane.