胸椎旁阻滞治疗白血病患者胸椎旁肿块引起的慢性疼痛

A. Ghidan, H. Abu Khudair, E. Farhoud
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引用次数: 0

摘要

镇痛。方法治疗对药物治疗无反应的女性PHN患者2例,56例,74例;疼痛局限于胸前外侧区域,限制了同侧手臂的自由活动。疼痛强烈(NRS评分为8分和10分),刺痛和灼烧,在没有刺激和夜间没有缓解的情况下加剧。超声引导下,0.25%左布比卡因30 ml、地塞米松8 mg于5肋间隙行SAPB。结果两例患者均即刻缓解疼痛:10分钟后NRS为2 ~ 3,2小时后NRS为0 ~ 1。随着时间的推移,获益基本保持:在48小时时,第一位患者疼痛恢复为轻度(NRS 2),第二位患者疼痛恢复为中度(NRS 4-5);在这个病人中,我们决定再进行一次注射。NRS最终降至2 ~ 3,无需再注射。两个月后,两种疼痛都消失了。结论长效SAPB联合局麻和类固醇治疗难治性PHN是一种安全有效的方法,应尽早行SAPB,避免慢性疼痛的发生,改善患者的生活质量和预后。需要进一步的研究来证实我们的初步数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
79 Thoracic paravertebral block for chronic pain caused by thoracic paravertebral mass in leukemia patient
analgesia. Methods We treated 2 female patients with PHN, unresponsive to medical therapies, 56 and 74 yo; pain was localized in the antero-lateral area of thorax, limiting free movements of ipsilateral arm. Pain was strong (NRS score 8 and 10), stabbing and burning, exacerbating in absence of stimuli and without relief during the night. We performed an ultrasound-guided SAPB with 0.25%-levobupivacaine 30 ml and dexamethasone 8 mg at 5 intercostal space. Results Both patients had immediate pain relief: NRS was 2–3 after 10 minutes, 0–1 after 2 hours. Benefit was substantially maintained over time: at 48 hours, resumption of pain was mild (NRS 2) in the first patient, moderate (NRS 4–5) in the second; in this patient we decided to perform another injection. NRS finally decreased to 2–3 and there was no need for further injections. At two months there was absence of pain for both. Conclusions Long-lasting SAPB with local anesthetic and steroids could be a safe and effective way to treat resistant PHN, and it should be performed as soon as possible to avoid incipit of chronic pain and improve patient quality of life and outcome. Further studies are necessary to confirm our preliminary data.
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