A. Olowokere, R. Olofinbiyi, A. Olajubu, B. Olofinbiyi
{"title":"尼日利亚埃基蒂州埃基蒂州立大学教学医院孕妇中与先兆子痫相关的患病率、危险因素和胎儿结局","authors":"A. Olowokere, R. Olofinbiyi, A. Olajubu, B. Olofinbiyi","doi":"10.4103/njhs.njhs_11_16","DOIUrl":null,"url":null,"abstract":"Background: Pre-eclampsia is one of the leading causes of maternal and perinatal morbidity and mortality globally. There is a paucity of data regarding pre-eclampsia and associated risk factors in Ekiti State, Nigeria. Objective: The aim was to assess the prevalence of pre-eclampsia, the associated risk factors and foetomaternal outcomes among women who delivered in the Teaching Hospital in Ekiti State. Materials and Methods: Case notes of women who delivered in the hospital between 1st January, 2010, and 31st December, 2014, were retrospectively reviewed and relevant data extracted and entered into a standardised pro forma. Data were analysed using descriptive and inferential statistics in the Statistical Package for the Social Sciences for Windows version 20. Relationships between variables were determined using Pearson correlation while Student t-test was used to assess differences between two means. The level of statistical significance was set at P< 0.05. Results: One hundred and forty-six (1.9%) of the 7709 women who delivered in the hospital during the 5-year period developed pre-eclampsia. One hundred and twenty (86.3%) of the 146 case notes were available for analysis. The mean age of respondents was 30 (5.2) years. There was a weak but significant correlation between parity and systolic blood pressure (BP) (r = 0.20, P = 0.02). A higher mean systolic and diastolic BP was recorded among unbooked women compared with booked women. The study showed that unbooked women had statistically significantly higher mean systolic (t = 2.69, P = 0.01) and diastolic (t = 3.03, P = 0.01) BP. The most common foetomaternal morbidities were birth asphyxia in 25 (19.8%), eclampsia in 23 (18.3%) and post-partum haemorrhage in 5 (3.9%). The maternal and foetal mortality were rates of 3.2% and 4.8%, respectively. Conclusion: Pre-eclampsia was a major contributor to maternal and perinatal morbidity and mortality in Ekiti State. Interventions to address pre-eclampsia should focus on early booking and prompt identification of women at risk for appropriate management and support.","PeriodicalId":19310,"journal":{"name":"Nigerian Journal of Health and Biomedical Sciences","volume":"73 1","pages":"7 - 13"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Prevalence, risk factors and foetomaternal outcomes associated with pre-eclampsia among pregnant women in Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria\",\"authors\":\"A. Olowokere, R. Olofinbiyi, A. Olajubu, B. Olofinbiyi\",\"doi\":\"10.4103/njhs.njhs_11_16\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Pre-eclampsia is one of the leading causes of maternal and perinatal morbidity and mortality globally. There is a paucity of data regarding pre-eclampsia and associated risk factors in Ekiti State, Nigeria. Objective: The aim was to assess the prevalence of pre-eclampsia, the associated risk factors and foetomaternal outcomes among women who delivered in the Teaching Hospital in Ekiti State. Materials and Methods: Case notes of women who delivered in the hospital between 1st January, 2010, and 31st December, 2014, were retrospectively reviewed and relevant data extracted and entered into a standardised pro forma. Data were analysed using descriptive and inferential statistics in the Statistical Package for the Social Sciences for Windows version 20. Relationships between variables were determined using Pearson correlation while Student t-test was used to assess differences between two means. The level of statistical significance was set at P< 0.05. Results: One hundred and forty-six (1.9%) of the 7709 women who delivered in the hospital during the 5-year period developed pre-eclampsia. One hundred and twenty (86.3%) of the 146 case notes were available for analysis. The mean age of respondents was 30 (5.2) years. There was a weak but significant correlation between parity and systolic blood pressure (BP) (r = 0.20, P = 0.02). A higher mean systolic and diastolic BP was recorded among unbooked women compared with booked women. The study showed that unbooked women had statistically significantly higher mean systolic (t = 2.69, P = 0.01) and diastolic (t = 3.03, P = 0.01) BP. The most common foetomaternal morbidities were birth asphyxia in 25 (19.8%), eclampsia in 23 (18.3%) and post-partum haemorrhage in 5 (3.9%). The maternal and foetal mortality were rates of 3.2% and 4.8%, respectively. Conclusion: Pre-eclampsia was a major contributor to maternal and perinatal morbidity and mortality in Ekiti State. Interventions to address pre-eclampsia should focus on early booking and prompt identification of women at risk for appropriate management and support.\",\"PeriodicalId\":19310,\"journal\":{\"name\":\"Nigerian Journal of Health and Biomedical Sciences\",\"volume\":\"73 1\",\"pages\":\"7 - 13\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nigerian Journal of Health and Biomedical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/njhs.njhs_11_16\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nigerian Journal of Health and Biomedical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/njhs.njhs_11_16","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
摘要
背景:先兆子痫是全球孕产妇和围产期发病率和死亡率的主要原因之一。关于尼日利亚埃基蒂州先兆子痫和相关危险因素的数据缺乏。目的:目的是评估在埃基蒂州教学医院分娩的妇女中先兆子痫的患病率、相关危险因素和胎儿结局。材料和方法:回顾性分析2010年1月1日至2014年12月31日期间在该医院分娩的妇女的病例记录,提取相关数据并输入标准化表格。使用Windows版本20的社会科学统计软件包中的描述性和推断性统计对数据进行分析。变量之间的关系采用Pearson相关确定,而学生t检验用于评估两个平均值之间的差异。P< 0.05为差异有统计学意义的水平。结果:5年期间在该院分娩的7709名妇女中有146名(1.9%)出现先兆子痫。146例病例记录中有120例(86.3%)可用于分析。受访者的平均年龄为30岁(5.2岁)。胎次与收缩压(BP)有微弱但显著的相关性(r = 0.20, P = 0.02)。未登记妇女的平均收缩压和舒张压高于登记妇女。研究显示,未预约妇女的平均收缩压(t = 2.69, P = 0.01)和舒张压(t = 3.03, P = 0.01)均有统计学意义上的升高。最常见的产妇发病率是出生窒息25例(19.8%),子痫23例(18.3%),产后出血5例(3.9%)。产妇和胎儿死亡率分别为3.2%和4.8%。结论:先兆子痫是埃基蒂州孕产妇和围产期发病率和死亡率的主要因素。应对先兆子痫的干预措施应侧重于早期预约和迅速识别有风险的妇女,以便进行适当的管理和支持。
Prevalence, risk factors and foetomaternal outcomes associated with pre-eclampsia among pregnant women in Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria
Background: Pre-eclampsia is one of the leading causes of maternal and perinatal morbidity and mortality globally. There is a paucity of data regarding pre-eclampsia and associated risk factors in Ekiti State, Nigeria. Objective: The aim was to assess the prevalence of pre-eclampsia, the associated risk factors and foetomaternal outcomes among women who delivered in the Teaching Hospital in Ekiti State. Materials and Methods: Case notes of women who delivered in the hospital between 1st January, 2010, and 31st December, 2014, were retrospectively reviewed and relevant data extracted and entered into a standardised pro forma. Data were analysed using descriptive and inferential statistics in the Statistical Package for the Social Sciences for Windows version 20. Relationships between variables were determined using Pearson correlation while Student t-test was used to assess differences between two means. The level of statistical significance was set at P< 0.05. Results: One hundred and forty-six (1.9%) of the 7709 women who delivered in the hospital during the 5-year period developed pre-eclampsia. One hundred and twenty (86.3%) of the 146 case notes were available for analysis. The mean age of respondents was 30 (5.2) years. There was a weak but significant correlation between parity and systolic blood pressure (BP) (r = 0.20, P = 0.02). A higher mean systolic and diastolic BP was recorded among unbooked women compared with booked women. The study showed that unbooked women had statistically significantly higher mean systolic (t = 2.69, P = 0.01) and diastolic (t = 3.03, P = 0.01) BP. The most common foetomaternal morbidities were birth asphyxia in 25 (19.8%), eclampsia in 23 (18.3%) and post-partum haemorrhage in 5 (3.9%). The maternal and foetal mortality were rates of 3.2% and 4.8%, respectively. Conclusion: Pre-eclampsia was a major contributor to maternal and perinatal morbidity and mortality in Ekiti State. Interventions to address pre-eclampsia should focus on early booking and prompt identification of women at risk for appropriate management and support.