Fabrication of AgOx/Graphene-Based Acetaminophen Sensor

In this work, we prepared AgOx/Graphene composite material as the working electrode; the acetaminophen is determined by the electrochemical method. Using cyclic voltammetry electrochemical sensing method determined the current signal of acetaminophen (0.98 μM–15.6 μM) with electrolyte phosphate-buffer solution. When the voltage was operated as 0.42 V, an oxidation peak appeared in the linear concentration range and the least mean square was obtained R2 = 0.9922, and the detection limit was calculated as 0.26 μM. Using a differential pulse voltammetry electrochemical-sensing method, we determined the current signal of various acetaminophen concentrations (0.98 μM–7.8 μM). When the voltage is 0.33 V, R2 = 0.9996, and the detection limit is 0.15 μM. The material was characterized by TEM and XRD. It was also confirmed that Ag2O and Ag coexist (AgOx) on the surface of graphene, which facilitates the oxidation-reduction reaction of acetaminophen on the electrode.