一个双种族青年队列的社会经济轨迹和高血压事件

K. Matthews, C. Kiefe, C. Lewis, Kiang Liu, S. Sidney, C. Yunis
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引用次数: 105

摘要

我们评估了最初的社会经济地位和10年间社会经济地位的变化,即社会经济地位轨迹,对黑人和白人年轻男性和女性原发性高血压发展的影响。在研究开始时,年龄在18至30岁之间的三千八百二十七名血压正常的人被随访了10年,在0、2、5、7和10年测量血压、体重指数和社会经济地位特征。社会经济地位轨迹测量是在10年级获得新的教育学位;2至10年级的基本生活费用难以支付;从第5年到第10年的收入类别变化,与第0年的状态有关。高血压被定义为收缩压≥140,舒张压≥90,或在第10年使用抗高血压药物。在研究开始时报告支付基本费用的困难(优势比=1.45,95%可信区间,1.05至2.02)和在第2年至第10年随访期间持续的困难(优势比=1.62,95%可信区间,1.04至2.53)与高血压事件独立相关,并根据种族-性别群体、体重指数、部位、年龄和初始收缩压进行调整。5 ~ 10年级收入下降倾向于与高血压相关,P =0.07,但学习开始后新的教育程度与高血压无关。社会经济发展轨迹与高血压发病率独立相关。社会经济地位的动态指数可能是一个有用的概念,以了解社会经济地位对高血压的自然历史的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Socioeconomic Trajectories and Incident Hypertension in a Biracial Cohort of Young Adults
We assessed the impact of initial socioeconomic status and change in socioeconomic status across 10 years, ie, status trajectories, on the development of essential hypertension among black and white young men and women. Three thousand eight hundred twenty-seven normotensive individuals ages 18 to 30 years at study entry were followed for 10 years, with blood pressure, body mass index, and socioeconomic status characteristics measured at years 0, 2, 5, 7, and 10. Socioeconomic status trajectory measures were a new educational degree earned by year 10; difficulties paying for basics during years 2 to 10; and change in income category from year 5 to 10, defined in relation to year 0 status. Hypertension was defined as systolic blood pressure ≥140, diastolic blood pressure ≥90, or antihypertensive medication use at year 10. Reporting difficulties paying for basics at study entry (odds ratio=1.45, 95% confidence interval, 1.05 to 2.02) and continued difficulties during year 2 to 10 follow-up (odds ratio=1.62, 95% confidence interval, 1.04 to 2.53) were independently associated with incident hypertension, adjusted for race-gender group, body mass index, site, age, and initial systolic blood pressure. Decline in income from year 5 to 10 tended to be associated with hypertension, P =0.07, but a new educational degree after study onset was not. Socioeconomic trajectories are independently associated with incidence of hypertension. A dynamic index of socioeconomic status may be a useful concept in understanding the effects of socioeconomic status on the natural history of hypertension.
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