重新发现CNN对原始电子健康记录的基于文本编码的多功能性

Eunbyeol Cho, Min Jae Lee, Kyunghoon Hur, Jiyoun Kim, Jinsung Yoon, E. Choi
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引用次数: 0

摘要

在电子病历中充分利用丰富的信息已迅速成为医疗领域的一个重要课题。最近的工作提出了一个很有前途的框架,它可以在原始EHR数据中嵌入整个功能,而不考虑其形式和医疗代码标准。然而,该框架只关注以最少的预处理对EHR进行编码,而没有考虑如何在计算和内存使用方面学习有效的EHR表示。在本文中,我们寻找一种多功能编码器,既可以将大数据减少到可管理的大小,又可以很好地保留患者的核心信息,以执行各种临床任务。我们发现,即使使用更少的参数和更少的训练时间,分层结构的卷积神经网络(CNN)在重建、预测和生成等各种任务上的表现往往优于最先进的模型。此外,事实证明,利用电子病历数据固有的层次结构可以提高任何类型的骨干模型和执行临床任务的性能。通过大量的实验,我们提出了具体的证据,将我们的研究结果推广到现实世界的实践中。我们给出了一个明确的指导方针,基于在探索众多设置时捕获的研究结果构建编码器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rediscovery of CNN's Versatility for Text-based Encoding of Raw Electronic Health Records
Making the most use of abundant information in electronic health records (EHR) is rapidly becoming an important topic in the medical domain. Recent work presented a promising framework that embeds entire features in raw EHR data regardless of its form and medical code standards. The framework, however, only focuses on encoding EHR with minimal preprocessing and fails to consider how to learn efficient EHR representation in terms of computation and memory usage. In this paper, we search for a versatile encoder not only reducing the large data into a manageable size but also well preserving the core information of patients to perform diverse clinical tasks. We found that hierarchically structured Convolutional Neural Network (CNN) often outperforms the state-of-the-art model on diverse tasks such as reconstruction, prediction, and generation, even with fewer parameters and less training time. Moreover, it turns out that making use of the inherent hierarchy of EHR data can boost the performance of any kind of backbone models and clinical tasks performed. Through extensive experiments, we present concrete evidence to generalize our research findings into real-world practice. We give a clear guideline on building the encoder based on the research findings captured while exploring numerous settings.
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