一种专用圆形线圈的设计,用于小型幻影和动物采集的3特斯拉磁共振临床扫描仪的磁共振光谱研究

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
G. Giovannetti, A. Flori, D. De Marchi, D. Montanaro, F. Frijia
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引用次数: 0

摘要

摘要简介:磁共振波谱(MRS)是一种非常强大的工具来探索组织成分,通过允许分子的选择性鉴定和分子分布作图。由于固有的信噪比限制(SNR),用临床扫描仪对小型幽灵和动物进行MRS需要设计和开发专用射频(RF)线圈,这是一项至关重要的任务。在这篇文章中,作者描述了一种1H发射/接收圆形线圈的模拟、设计和应用,该线圈适用于使用临床3T扫描仪对小型幻影和小动物模型进行MRS研究。特别是,圆形线圈可以改善肿瘤研究的动物实验,其中病变定位在特定区域。材料和方法:利用毕奥-萨瓦定律计算磁场图,用解析法计算电感值。最后,用微扰球法测量了线圈的灵敏度。随后,建立了线圈的原型,并在工作台上通过采集MRS数据进行了测试。结果:在这项工作中,我们展示了设计权衡,成功地开发了一种专用线圈,用于用临床扫描仪在小幽灵和动物中进行MRS实验。研究中设计的线圈提供了获得高信噪比和良好光谱分辨率的MRS数据的潜力。结论:本文提供了专用圆形线圈的设计,建模和构造的详细信息,该线圈代表了低成本和易于构建的答案,用于临床扫描仪的小样本MRS实验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Design of a dedicated circular coil for Magnetic Resonance Spectroscopy studies in small phantoms and animal acquisition with a 3 Tesla Magnetic Resonance clinical scanner
Abstract Introduction: Magnetic Resonance Spectroscopy (MRS) is a very powerful tool to explore the tissue components, by allowing a selective identification of molecules and molecular distribution mapping. Due to intrinsic Signal-to-Noise Ratio limitations (SNR), MRS in small phantoms and animals with a clinical scanner requires the design and development of dedicated radiofrequency (RF) coils, a task of fundamental importance. In this article, the authors describe the simulation, design, and application of a 1H transmit/receive circular coil suitable for MRS studies in small phantoms and small animal models with a clinical 3T scanner. In particular, the circular coil could be an improvement in animal experiments for tumor studies in which the lesions are localized in specific areas. Material and methods: The magnetic field pattern was calculated using the Biot–Savart law and the inductance was evaluated with analytical calculations. Finally, the coil sensitivity was measured with the perturbing sphere method. Successively, a prototype of the coil was built and tested on the workbench and by the acquisition of MRS data. Results: In this work, we demonstrate the design trade-offs for successfully developing a dedicated coil for MRS experiments in small phantoms and animals with a clinical scanner. The coil designed in the study offers the potential for obtaining MRS data with a high SNR and good spectral resolution. Conclusions: The paper provides details of the design, modelling, and construction of a dedicated circular coil, which represents a low cost and easy to build answer for MRS experiments in small samples with a clinical scanner.
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来源期刊
Polish Journal of Medical Physics and Engineering
Polish Journal of Medical Physics and Engineering RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.30
自引率
0.00%
发文量
19
期刊介绍: Polish Journal of Medical Physics and Engineering (PJMPE) (Online ISSN: 1898-0309; Print ISSN: 1425-4689) is an official publication of the Polish Society of Medical Physics. It is a peer-reviewed, open access scientific journal with no publication fees. The issues are published quarterly online. The Journal publishes original contribution in medical physics and biomedical engineering.
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