心血管疾病中的抗衰老药物

R. Morishita, I. Komuro, M. Horiuchi, H. Nakagami, T. Minamino, Y. Higashi
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摘要

“一个人的年龄和他的动脉一样大。”这句话是威廉·奥斯勒在1898年说的,现在仍然被许多研究人员和临床医生当作一句诙谐的话来使用。它构成了抗衰老的核心概念。他的这句话已经过去了大约100年,当我们生活在一个食物丰富的时代,我们现在才真正理解他的话有多重要。在常规医学检查和会诊中,通过测量血管功能计算血管年龄值的应用逐渐增多。从现在起,越来越重要的是将这些数据与实际战略联系起来,以延长与健康相结合的寿命,即预防疾病和减少与缺血性疾病有关的事件。对于这种联系,积累血管衰老的基础和临床科学证据被认为是必不可少的。在本次研讨会上,基础和临床方面的相关领域的专家聚集在一起,以心血管疾病的抗衰老医学为主题,就“什么是血管衰老?”,对主要涉及血管的其他疾病以及抗衰老措施、肾素-血管紧张素系统和其他相关主题之间的关系进行分析。我们希望观众能从中获得一些有趣的发现,这些发现可能会应用到他们的日常研究中,并获得对他们的医疗实践有帮助的知识。认知功能和血管紧张素受体亚型
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anti-Aging Medicine in Cardiovascular Disease
“A man is as old as his arteries.” This statement was made by William Osler in 1898 and is still currently used by many researchers and clinicians as a witty remark. It constitutes a core concept of Anti-Aging. About 100 years has passed since he made this remark, and as we live in an age of plentiful food we now really understand how significant his statement is. The use of vascular age values calculated from measurement of vascular functions has gradually been increasing in routine medical examination and consultation. From now on, it will be increasingly important to link these data to practical strategies for the purpose of improving longevity coupled with health, i.e., for prevention of diseases and reduction of events related to ischemic diseases. For such linking, it is considered essential to accumulate both basic and clinical scientific evidence for vascular senescence. In this symposium, specialists in the concerned fields on both the basic and clinical sides have gathered to provide state-of-the-art knowledge under the theme of Anti-Aging Medicine in Cardiovascular Disease and regarding the question, “What is vascular senescence?”, conducting analyses of association with other diseases primarily involving blood vessels and the relationships between Anti-Aging measures, the renin-angiotensin system, and other relevant topics. We hope that the audience will pick up interesting findings that may be implemented in their daily research and acquire knowledge that will be helpful in their medical practices. Cognitive Function and Angiotensin Receptor Subtypes
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