在布拉柴维尔食用的三种叶类蔬菜配方对wistar大鼠生殖功能的影响

Bml Peneme, LR Miamb, O. A. Etou, D. Lepondo, H. Akassa, A. Abena
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引用次数: 0

摘要

菠菜、藜科的苋菜和芸苔科的油菜是布拉柴维尔因其营养价值而被食用的蔬菜。本研究的目的是评价以这三种叶类蔬菜为基础的配方对生殖功能的影响。给药剂量分别为250、500、1000 mg/Kg的雄性和雌性大鼠。该配方对男性的壮阳作用通过性坐骑、勃起次数、射精次数和潜伏期进行评估;女性的雌激素活动,是基于性周期的变化,阴道的状态和宫颈粘液。急性毒性试验结果表明,复方水提物(EA)对小鼠的一般状况和行为无明显影响,无死亡记录。在雄性大鼠中,500 mg/Kg的配方提取物显著增加了性交次数、勃起次数和射精次数;并且减少了延迟时间。在雌性中,500 mg/kg剂量的提取物导致发情期和前发情期周期阻滞,宫颈粘液增加,阴道开口增加。雌二醇水平也增加了。在该提取物中观察到的黄酮类化合物、皂苷类和类固醇可能是对雄性和雌性大鼠的性参数产生影响的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of a recipe based on three leafy vegetables consumed in Brazzaville on the reproductive function of the wistar rat
Spinacia oleracea, Amaranthus hybridus of the Chenopodiaceae family and Brassica campestris of the Brassicaceae family are vegetables consumed in Brazzaville for their nutritional virtues. The aim of this study is to evaluate the effects of the recipe based on these three leafy vegetables on reproductive functions. The recipe at doses of 250, 500 and 1000 mg/Kg was administered to male and female rats. The aphrodisiac effects of the recipe in males were evaluated on the numbers of sexual mounts, erections, ejaculations, and latency time; and the estrogenic activities in females, based on the variation of the sexual cycle, the state of the vaginal meatus and the cervical mucus. On acute toxicity, the results show that the aqueous extract (EA) of the recipe does not alter the general condition and behaviour of mice, and no mortality was recorded. In male rats the 500 mg/Kg recipe extract significantly increased the number of sexual mounts, erections, and ejaculations; and decreased the latency time. In females, the 500 mg/kg dose of the extract caused blocking of the cycle in oestrus and pro-oestrus, with increased cervical mucus and vaginal opening. Estradiol levels were also increased. The flavonoids, saponosides and steroids observed in this extract could be responsible for the effects observed on the sexual parameters studied in male and female rats.
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