Nedeni bilinmeyen ateşle başvuran opere doğuştan kalp hastalığı olan hastada Coxiella Burnetii endokarditi

Q fever is a zoonotic infection caused by Coxiella Burnetii Although it is usually asymptomatic acute form of disease may change from flu like illness to severe pneumonia Chronic form may present with vascular disease or endocarditis A 6 year old female patient from Sudan followed with the diagnosis of pulmonary atresia and ventricular septal defect was referred to our department because of stenosis in the conduit placed to right ventricular outflow during Rastelli operation performed in Sudan Six months ago in Jordan stenting was performed for conduit stenosis but was unsuccessful Because of long lasting fever she was treated for culture negative endocarditis in Sudan In physical examination fever and hepatosplenomegaly were present Laboratory findings revealed anemia leukopenia Coombs rsquo; positivity hypergamaglobulinemia and positive anticardiolipin antibodies but blood cultures were negative Different antibiotic protocols were administered for culture negative endocarditis for 2 months but fever persisted On 67 day of hospitalization positive antibody titers for Coxiella Burnetii were detected and doxycycline and hydroxychloroquine were started Here a case of chronic Q fever due to Coxiella burnetii which is a rare cause of culture negative endocarditis is presented Turk Arch Ped 2013; 48: 339 41