Chun-Hsiang Hu, T. Hsu, Kuan-Sheng Chen, Wei-Ming Lee, Hsien-Chi Wang
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引用次数: 1
摘要
为了评估腹部手术中体积变异性指数(PVI)引导的液体治疗对组织灌注的血流动力学优化效果,将19只接受择期腹部手术的客户犬随机分为对照组(n=10)和PVI组(n=9)。在对照组中,围手术期液体管理基于2013年AAHA/AAFP犬猫液体治疗指南。在PVI组,液体量维持在基本的每日需水量。若PVI高于15%持续>5min,则给予3-5mL /kg结晶液丸。分别于插管、拔管时及术后6、12、24h测定组织灌注指标乳酸水平。对照组和PVI组总输注量和平均输注量无显著差异。对照组术后12h乳酸水平显著高于PVI组(2.2±1.0mmol/L vs 1.1±0.6mmol/L, p=0.008),术后总体(1.8±0.8mmol/L vs 1.2±0.5m)。
PLETH VARIABILITY INDEX-GUIDED FLUID THERAPY LOWERS POST-OPERATIVE LACTATE LEVELS IN DOGS UNDERGOING ELECTIVE ABDOMINAL SURGERY: A RANDOMIZED CONTROLLED TRIAL
To evaluate the hemodynamic optimization effect of pleth variability index (PVI)-guided fluid therapy during abdominal surgery on tissue perfusion, 19 client-owned dogs that underwent elective abdominal surgery were randomized into control (n=10) and PVI (n=9) groups. In the control group, perioperative fluid management was based on the 2013 AAHA/AAFP Fluid Therapy Guidelines for Dogs and Cats. In the PVI group, the fluid rate was maintained based on basic daily requirements. If PVI was higher than 15% for >5min, 3–5mL/kg of crystalloid fluid bolus was infused. The tissue perfusion indicator, lactate levels, was measured at the time of intubation, extubation, and 6, 12 and 24h postoperatively. There were no significant differences in total and average fluid infused between control and PVI groups. The control group had significantly higher lactate levels than that of the PVI group at 12h postoperatively (2.2±1.0mmol/L versus 1.1±0.6mmol/L, p=0.008) and overall postoperatively (1.8±0.8mmol/L versus 1.2±0.5m...