{"title":"纤维蛋白胶在颞透明角膜隧道切口中的应用","authors":"Burkhard Dick, Thomas Kohnen, Volker Hessemer","doi":"10.1016/S0955-3681(13)80039-1","DOIUrl":null,"url":null,"abstract":"<div><p><strong>OBJECTIVE:</strong> While 3.5 mm clear corneal incisions for the implantation of foldable silicone lenses are commonly accepted, longer incisions for PMMA-IOL implantation are associated with a possibly higher risk of infection and less self-sealing properties. <strong>DESIGN:</strong> It was intended to reinforce the 5 mm clear corneal tunnel incision after phacoemulsification and IOL-implantation with fibrin adhesive. <strong>SETTING:</strong> Department of Ophthalmology, University of Giessen, Germany. <strong>METHODS:</strong> Upon simultaneous mixing of fibrinogen complex and thrombin, the final stages of the coagulation cascade are mimicked after application of fibrin glue, resulting in formation of a fibrin clot. <strong>MAIN OUTCOME:</strong> The sealant consolidated and adhered to the site of corneal application. The present case demonstrated that fibrin glue is efficacious in watertight wound closure of 5 mm clear corneal incision and provides good support for corneal healing. Only minimal surgically-induced with-the-rule astigmatism was observed. <strong>CONCLUSION:</strong> In the future, this technique of corneal wound closure might develop as an alternative to singlesuture wound closure after small incision cataract extraction.</p></div>","PeriodicalId":100500,"journal":{"name":"European Journal of Implant and Refractive Surgery","volume":"7 4","pages":"Pages 224-228"},"PeriodicalIF":0.0000,"publicationDate":"1995-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0955-3681(13)80039-1","citationCount":"2","resultStr":"{\"title\":\"Fibrin Glue in Temporal Clear Corneal Tunnel Incision\",\"authors\":\"Burkhard Dick, Thomas Kohnen, Volker Hessemer\",\"doi\":\"10.1016/S0955-3681(13)80039-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><strong>OBJECTIVE:</strong> While 3.5 mm clear corneal incisions for the implantation of foldable silicone lenses are commonly accepted, longer incisions for PMMA-IOL implantation are associated with a possibly higher risk of infection and less self-sealing properties. <strong>DESIGN:</strong> It was intended to reinforce the 5 mm clear corneal tunnel incision after phacoemulsification and IOL-implantation with fibrin adhesive. <strong>SETTING:</strong> Department of Ophthalmology, University of Giessen, Germany. <strong>METHODS:</strong> Upon simultaneous mixing of fibrinogen complex and thrombin, the final stages of the coagulation cascade are mimicked after application of fibrin glue, resulting in formation of a fibrin clot. <strong>MAIN OUTCOME:</strong> The sealant consolidated and adhered to the site of corneal application. The present case demonstrated that fibrin glue is efficacious in watertight wound closure of 5 mm clear corneal incision and provides good support for corneal healing. Only minimal surgically-induced with-the-rule astigmatism was observed. <strong>CONCLUSION:</strong> In the future, this technique of corneal wound closure might develop as an alternative to singlesuture wound closure after small incision cataract extraction.</p></div>\",\"PeriodicalId\":100500,\"journal\":{\"name\":\"European Journal of Implant and Refractive Surgery\",\"volume\":\"7 4\",\"pages\":\"Pages 224-228\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1995-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0955-3681(13)80039-1\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Implant and Refractive Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0955368113800391\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Implant and Refractive Surgery","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0955368113800391","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fibrin Glue in Temporal Clear Corneal Tunnel Incision
OBJECTIVE: While 3.5 mm clear corneal incisions for the implantation of foldable silicone lenses are commonly accepted, longer incisions for PMMA-IOL implantation are associated with a possibly higher risk of infection and less self-sealing properties. DESIGN: It was intended to reinforce the 5 mm clear corneal tunnel incision after phacoemulsification and IOL-implantation with fibrin adhesive. SETTING: Department of Ophthalmology, University of Giessen, Germany. METHODS: Upon simultaneous mixing of fibrinogen complex and thrombin, the final stages of the coagulation cascade are mimicked after application of fibrin glue, resulting in formation of a fibrin clot. MAIN OUTCOME: The sealant consolidated and adhered to the site of corneal application. The present case demonstrated that fibrin glue is efficacious in watertight wound closure of 5 mm clear corneal incision and provides good support for corneal healing. Only minimal surgically-induced with-the-rule astigmatism was observed. CONCLUSION: In the future, this technique of corneal wound closure might develop as an alternative to singlesuture wound closure after small incision cataract extraction.