非手术治疗稳定性幼年性膝关节剥离性骨软骨炎:卸载支架的疗效。

Frances A. Tepolt, L. Kalish, B. Heyworth, M. Kocher
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引用次数: 9

摘要

本研究的目的是比较一个大型队列中使用卸载支架非手术治疗与不使用卸载支架的其他非手术治疗方式治疗的膝关节稳定性幼年性夹层性骨软骨炎(JOCD)的治疗结果。本回顾性研究评估了在单一机构接受至少3个月非手术治疗股骨髁稳定性JOCD的骨骼未成熟患者的临床病程(2001-2014)。治疗是基于医生的偏好。卸载支架与其他“非卸载”方式进行比较,成功的非手术治疗定义为避免后续手术干预。纳入298例患者,其中219例(73%)为男性。诊断时的平均±SD年龄为11.5±1.6岁。35例患者被诊断为双侧强迫症,共造成333个膝关节。187例(56%)膝关节采用卸载支架治疗至少3个月,146例(44%)膝关节采用其他非手术方式治疗。所有患者均接受活动限制治疗。共有83例(25%)病例采用了负重限制,持续时间为19至196天(中位数:46天),各组间的限制率相似。189例(57%)膝关节非手术治疗成功,中位随访9.5个月(四分位数范围:5.9-15.7个月)。144例(43%)膝关节需要手术治疗,中位时间为6.0个月(四分位数范围:4.1-10.5个月)。与非卸载支架组相比,卸载支架组更频繁地需要手术干预[分别为93/187(50%)和51/146(35%)个膝关节;p = 0.02]。男性(P = 0.05)和Hefti分期(P = 0.05)可能与非手术治疗成功相关。在57%的病例中,非手术治疗稳定型JOCD可避免后续手术干预。与其他非手术方式相比,卸荷式支具并不能显著改善预后。证据级别:III回顾性比较病例系列。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nonoperative treatment of stable juvenile osteochondritis dissecans of the knee: effectiveness of unloader bracing.
The purpose of this study was to compare the treatment outcomes of stable juvenile osteochondritis dissecans (JOCD) of the knee in a large cohort treated nonoperatively with unloader bracing versus other nonoperative treatment modalities without unloader bracing. This retrospective study assessed the clinical course of skeletally immature patients who underwent a minimum of 3 months nonoperative treatment for stable JOCD of the femoral condyle at a single institution (2001-2014). Treatment was based on physician preference. Unloader bracing was compared with other 'non-unloader' modalities, with successful nonoperative treatment defined as the avoidance of subsequent surgical intervention. Two hundred ninety-eight patients were included, 219 (73%) of whom were male. The mean ± SD age at diagnosis was 11.5 ± 1.6 years. Thirty-five patients were diagnosed with bilateral OCD, resulting in 333 knees in total. One hundred eighty-seven (56%) knees were treated with unloader bracing for a minimum of 3 months, whereas 146 (44%) were treated with other nonoperative modalities. All patients were treated with activity restrictions. Weight-bearing restrictions were applied for a total of 83 (25%) cases, for durations ranging from 19 to 196 days (median: 46 days) and at similar rates across groups. Nonoperative treatment was successful in 189 (57%) knees with a median follow-up of 9.5 months (interquartile range: 5.9-15.7 months). Surgical intervention was required in 144 (43%) knees at a median time of 6.0 months (interquartile range: 4.1-10.5 months). The unloader bracing group more often required surgical intervention when compared with the nonunloader group [93/187 (50%) vs. 51/146 (35%) knees, respectively; P = 0.02]. Male sex (P = 0.05) and Hefti stage I (P = 0.05) showed possible associations with nonoperative treatment success. Nonoperative treatment for stable JOCD of the knee leads to the avoidance of subsequent surgical intervention in 57% of cases. Unloader bracing is not associated with significantly improved outcomes when compared with other nonoperative modalities. Level of Evidence: III Retrospective Comparative Case Series.
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