免疫“Gam-COVID-Vac”和COVID-19患者的体液反应特征

Q4 Health Professions

Klinichescheskaya Laboratornaya Diagnostika Pub Date : 2022-04-17 DOI:10.51620/0869-2084-2022-67-4-227-233

Yuliya Aleksandrovna Akinshina, S. Mardanly, S. Rotanov, V. V. Pomazanov, V. A. Kiseleva, I. I. Ermolaev

{"title":"免疫“Gam-COVID-Vac”和COVID-19患者的体液反应特征","authors":"Yuliya Aleksandrovna Akinshina, S. Mardanly, S. Rotanov, V. V. Pomazanov, V. A. Kiseleva, I. I. Ermolaev","doi":"10.51620/0869-2084-2022-67-4-227-233","DOIUrl":null,"url":null,"abstract":"The paper present the results of a survey of people who have undergone immunization with a combined vector vaccine for the prevention of coronavirus infection COVID-19 «Sputnik V - Gam-COVID-Vac», as well as COVID-19 recovalents. Using a quantitative enzyme-linked immunosorbent assay, the levels of specific IgG were determined in persons who had had different degrees of severity before vaccination, in persons who were immuno-negative before immunization, as well as in convalescents who had undergone coronavirus infection of varying severity. The immunological targeting of antibodies against various SARS-CoV-2 proteins is considered.","PeriodicalId":52451,"journal":{"name":"Klinichescheskaya Laboratornaya Diagnostika","volume":"61 1","pages":"227-233"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Features of the humoral response to immunization \\\"Gam-COVID-Vac\\\" and in patients with COVID-19.\",\"authors\":\"Yuliya Aleksandrovna Akinshina, S. Mardanly, S. Rotanov, V. V. Pomazanov, V. A. Kiseleva, I. I. Ermolaev\",\"doi\":\"10.51620/0869-2084-2022-67-4-227-233\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The paper present the results of a survey of people who have undergone immunization with a combined vector vaccine for the prevention of coronavirus infection COVID-19 «Sputnik V - Gam-COVID-Vac», as well as COVID-19 recovalents. Using a quantitative enzyme-linked immunosorbent assay, the levels of specific IgG were determined in persons who had had different degrees of severity before vaccination, in persons who were immuno-negative before immunization, as well as in convalescents who had undergone coronavirus infection of varying severity. The immunological targeting of antibodies against various SARS-CoV-2 proteins is considered.\",\"PeriodicalId\":52451,\"journal\":{\"name\":\"Klinichescheskaya Laboratornaya Diagnostika\",\"volume\":\"61 1\",\"pages\":\"227-233\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Klinichescheskaya Laboratornaya Diagnostika\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51620/0869-2084-2022-67-4-227-233\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Health Professions\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Klinichescheskaya Laboratornaya Diagnostika","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51620/0869-2084-2022-67-4-227-233","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Health Professions","Score":null,"Total":0}

引用次数: 0

摘要

本文介绍了预防冠状病毒感染的COVID-19“Sputnik V - Gam-COVID-Vac”联合载体疫苗免疫接种人群以及COVID-19恢复价的调查结果。采用定量酶联免疫吸附试验，对接种疫苗前有不同严重程度的人、接种疫苗前免疫阴性的人以及不同严重程度的冠状病毒感染的康复者进行特异性IgG水平测定。考虑了针对各种SARS-CoV-2蛋白的抗体的免疫靶向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Features of the humoral response to immunization "Gam-COVID-Vac" and in patients with COVID-19.

The paper present the results of a survey of people who have undergone immunization with a combined vector vaccine for the prevention of coronavirus infection COVID-19 «Sputnik V - Gam-COVID-Vac», as well as COVID-19 recovalents. Using a quantitative enzyme-linked immunosorbent assay, the levels of specific IgG were determined in persons who had had different degrees of severity before vaccination, in persons who were immuno-negative before immunization, as well as in convalescents who had undergone coronavirus infection of varying severity. The immunological targeting of antibodies against various SARS-CoV-2 proteins is considered.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Klinichescheskaya Laboratornaya Diagnostika Health Professions-Medical Laboratory Technology

CiteScore

0.90

自引率

0.00%

发文量

110

期刊介绍： The journal deals with theoretical and practical problems of clinical laboratory diagnosis, publishes editorial articles, reviews of literature, original articles, short reports, discussions, book reviews, current events, materials which may assist the practitioners, methods of laboratory investigations used in medicine, materials on the results of practical application of new methods of investigation in the following fields of clinical laboratory diagnosis: hematology, cytology, coagulation, biochemistry, immunology.