用像素探测器Timepix检测强子治疗光束的一次和二次辐射并跟踪可视化

J. Jakubek, C. Granja, O. Jakel, M. Martišíková, Stanislav Pospicil
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引用次数: 20

摘要

物质中相对论能量的质子和强子束的相互作用伴随着穿透高能二次粒子和核反应产物的产生,这可以影响用于放射治疗目的的初级高LET粒子的能量的高度局部沉积。半导体像素探测器Timepix可直接提供由一次辐射产生和伴随的所有电离粒子的观测,以及粒子能量损失、轨迹、局部能量沉积和侧向散射的直接测量。该装置作为一种活性核乳液运行,提供粒子轨迹的在线可视化。本文介绍了在海德堡重离子治疗HIT装置中分别产生的能量范围为48-220 MeV/u和88-430 MeV的质子和碳离子束的中试实验结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detection and track visualization of primary and secondary radiation in hadron therapy beams with the pixel detector Timepix
The interaction of proton and hadron beams of relativistic energy in matter is accompanied by the production of penetrating highly energetic secondary particles and nuclear reaction products which can affect the desired highly localized deposition of energy of the primary high LET particles for radiotherapy purposes. The observation of all ionizing particles arising from and accompanying the primary radiation as well as the direct measurement of particle energy loss, trajectory, local energy deposition and lateral straggling can be directly provided by the semiconductor pixel detector Timepix. This device operates as an active nuclear emulsion providing on-line visualization of particle traces. Results of a pilot experiment are presented with proton and carbon ion beams in the energy range 48–220 MeV/u and 88–430 MeV, respectively produced at the Heavy Ion Therapy HIT facility in Heidelberg.
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