锗化合物及其在动物体内的作用

R. Fedoruk, I. Kovalchuk, L. M. Mezentseva, U. Tesarivska, A. Pylypets, V. Kaplunenko
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引用次数: 3

摘要

近年来对锗化合物对实验动物和生产动物的生物学影响进行了文献资料和单独的研究结果分析。本文阐述了无机锗和有机锗化合物在化学和生物技术合成中的比较作用,以及纳米技术柠檬酸锗对动物免疫、血液、抗氧化、解毒、生殖和神经系统功能的影响。本文论述了锗化合物的形态、剂量和暴露对动物机体的影响的不同。基于对自己和其他作者的研究结果的比较分析,强调了在化学、生物技术和纳米技术合成中使用有机锗化合物的好处。在动物短期和长期暴露于各种锗化合物后,对一个单独的身体器官、身体系统以及整个动物身体进行了功能分析。根据现有文献,对各种锗化合物的毒性、对动物生产能力和产品质量的影响进行了研究。比较了一些药物、生物活性添加剂和含锗化合物的产品对动物机体的影响。总结了酵母酵母生物技术合成的有机锗化合物和纳米技术合成的枸橼酸锗化合物的生物作用优势,并展望了其在畜牧兽医领域的应用前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Germanium compounds and their role in animal body
Last years literature data and separate research results analysis was carried out concerning biological influence of Germanium compounds at laboratory and productive animals. The article states a comparative effect of mineral and organic Germanium compounds in chemical and biotechnological synthesis, as well as nanotechnological germanium citrate influence on the functioning of the immune, hematological, antioxidant, detoxification, reproductive and nervous systems of animals. The article displays a difference in influence of Germanium compounds on animal body depending on its form, dose and exposure. Benefits of using organic Germanium compounds in chemical, biotechnological and nanotechnological synthesis are highlighted based on a comparative analysis of the own research results, as well as other authors. Functioning analysis of a separate body organs, body systems as well as animal body in total was conducted after animals been exposed to short-term and long-lasting action of various Germanium compounds. Studies results for various Germanium compounds toxicity, their impact on animal productivity and product quality are stated based on the available literature. Comparison of influence effect for some drugs, biologically active additives and products containing Germanium compounds on the animal body was documented. Conclusions are made about the advantages of biological action of organic Germanium compounds, made by biotechnological synthesis using yeast Saccharomyces cerevisiae, and Germanium citrate, obtained on the basis of nanotechnology, regarding the prospects of its use in animal husbandry and veterinary medicine.
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