{"title":"苦味酸法测定扑热息痛的电荷转移","authors":"N. Gloria","doi":"10.33552/APPR.2018.01.000507","DOIUrl":null,"url":null,"abstract":"A cost effective and sensitive spectrophotometric method has been developed for the assay of paracetamol in pure and commercial forms. The method employed was charge transfer complexation. Paracetamol formed a 1:2 stoichiometric ratio with picric acid. The complex was quantified at 500nm. Beer –Lambert’s law was obeyed within a concentration range of 5-10μg/ml with molar absorptivity of 2.6 x104Lmol-1cm-1. The method was used for the determination paracetamol in pure and commercial forms with percentage mean recovery of 95%.","PeriodicalId":8291,"journal":{"name":"Archives of Pharmacy & Pharmacology Research","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A Charge Transfer Determination of Paracetamol with Picric Acid\",\"authors\":\"N. Gloria\",\"doi\":\"10.33552/APPR.2018.01.000507\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A cost effective and sensitive spectrophotometric method has been developed for the assay of paracetamol in pure and commercial forms. The method employed was charge transfer complexation. Paracetamol formed a 1:2 stoichiometric ratio with picric acid. The complex was quantified at 500nm. Beer –Lambert’s law was obeyed within a concentration range of 5-10μg/ml with molar absorptivity of 2.6 x104Lmol-1cm-1. The method was used for the determination paracetamol in pure and commercial forms with percentage mean recovery of 95%.\",\"PeriodicalId\":8291,\"journal\":{\"name\":\"Archives of Pharmacy & Pharmacology Research\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Pharmacy & Pharmacology Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33552/APPR.2018.01.000507\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Pharmacy & Pharmacology Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33552/APPR.2018.01.000507","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Charge Transfer Determination of Paracetamol with Picric Acid
A cost effective and sensitive spectrophotometric method has been developed for the assay of paracetamol in pure and commercial forms. The method employed was charge transfer complexation. Paracetamol formed a 1:2 stoichiometric ratio with picric acid. The complex was quantified at 500nm. Beer –Lambert’s law was obeyed within a concentration range of 5-10μg/ml with molar absorptivity of 2.6 x104Lmol-1cm-1. The method was used for the determination paracetamol in pure and commercial forms with percentage mean recovery of 95%.
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