精确医学方法在2型糖尿病治疗中的进展:综述

E. Milla-Amekor, E. Ewusie
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引用次数: 0

摘要

预测表明,到2050年将有大约7亿人患有糖尿病,这一数字在过去20年中翻了一番。在精准医疗的帮助下,2型糖尿病治疗成本的上升可能会减少,现有的治疗差距可能会缩小。考虑到每个人独特的基因、环境和行为特征,精准医学是一种新的治疗方法。精准治疗的主要目标是准确预测病人对治疗的反应。由于它的适用范围很广,它可以作为一种对全体人口的预防策略。药物治疗、减肥、定期运动和营养饮食都可以预防2型糖尿病。优化代谢控制是这种糖尿病治疗有可能降低死亡率和提高生活水平的一种方式。转化卫生研究资金不足、数据格式不兼容、缺乏系统互操作性、缺乏决策支持系统以及缺乏IT基础设施支持,这些都是在临床实践中广泛应用精准医学技术的一些障碍。建立一个全球性的临床研究小组,致力于提高公众对精准医学在治疗糖尿病方面的巨大优势的理解和赞赏,有助于科学成果向实际应用的预测转化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in Precision Medicine Approaches for Type 2 Diabetes Management: A Comprehensive Review
Projections indicate that, approximately 700 million people will be living with diabetes by 2050, a figure that has doubled in the previous twenty years. The rising cost of type 2 diabetes care might be reduced and existing treatment gaps could be closed with the help of precision medicine. Taking into consideration each individual unique genetic, environmental, and behavioral characteristic, precision medicine is a new approach to treatment. The primary goal of precision medication is to accurately foresee how a patient will respond to treatment. It may be used as a prophylactic strategy for the whole population because of how broadly it applies. Medication, weight reduction, regular exercise, and a nutritious diet all work together to prevent type 2 diabetes. Optimizing metabolic control is one way in which this kind of diabetes therapy has a probability to reduce death rates and improve standard of life. Inadequate funding for translational health research, incompatible data formats, a lack of system interoperability, a lack of decision-making support systems, and a lack of IT infrastructure support are just some of the obstacles to the widespread utilization of precision medicine technologies in clinical practice. Forecast translation of scientific results into practical applications may be aided by the creation of a worldwide clinical studies group dedicated to raising public understanding and appreciation of the great advantages of precision medicine in treating diabetes.
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