伴有认知障碍的Susac综合征- 31岁女性1例报告

Michał Terpiłowski, Barbara Terpiłowska, Anna Orzeł, Dominika Szlichta, Marcin Łata, Michał Próchnicki
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引用次数: 0

摘要

摘要简介:Susac综合征(Susac syndrome)是一种罕见的由大脑、视网膜和内耳微血管闭塞引起的免疫介导性疾病。它的临床特征是脑病、视力障碍和听力丧失。SuS的诊断主要基于临床症状和支持性检查,其中MRI表现出特征性变化。病例报告:在这里,我们提出一个病例的病人可能SuS与精神症状。一名31岁妇女因精神健康恶化数周被送入精神科,表现为消极情绪和自杀念头。在住院期间,进行了神经学会诊,其中患者被确定为意识清醒,精神运动迟缓,语言交流受损,持续听力和视力障碍。认知功能的横断面评估显示,患者有神经心理缺陷的广泛性综合征,这证实了痴呆症的诊断。讨论:本病例摘要提供了一个被诊断为SuS的女性的例子,表现为认知障碍,并伴有视力和听力下降。值得强调的是,在发病时出现这种三联征是罕见的。核磁共振成像所描述的大脑有机变化的特征可能解释了该病例所描述的症状。SuS的预后取决于早期诊断和治疗。结论:在出现非特异性神经精神症状、进行性多灶性神经症状、听力损失和视力损害时,应始终考虑SuS的诊断。一个重要的事实是,在大多数情况下,典型的SuS三联症状不会同时发生,这使得诊断过程非常困难,并可能导致误诊。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Susac syndrome with cognitive impairment - case report of 31-year-old woman
Abstract Introduction: Susac syndrome (SuS) is a rare immune-mediated disease caused by occlusions of microvessels in the brain, retina and inner ear. It is characterized by the clinical triad of encephalopathy, visual disturbances and hearing loss. The diagnosis of SuS is based mainly on the clinical symptoms and the supporting tests in which characteristic changes occur in the MRI. Case report: Here, we present a case of a patient with possible SuS with psychiatric symptoms. A 31-year-old woman was admitted to the Department of Psychiatry due to deteriorating mental health for several weeks manifested as a negative mood and suicidal thoughts. During hospitalization, a neurological consultation was conducted, in which the patient was identified as conscious, psychomotor sluggish, with impaired verbal contact and persistent hearing and vision impairment. Cross-sectional assessment of cognitive functions revealed that the patient had a generalized syndrome of neuropsychological deficits, which confirms the diagnosis of dementia. Discussion: This case summary provides an example of a woman diagnosed with SuS manifested as a cognitive impairment with associated vision and hearing deterioration. It is worth emphasizing the fact that such presentation of the triad of at disease onset is rare. The characteristics of the organic changes in the brain described in the MRI probably explain the symptoms described in that case. The prognosis of SuS depends on early diagnosis and treatment. Conclusions: A diagnosis of SuS should always be considered in the presence of nonspecific neuropsychiatric symptoms and progressive multifocal neurological symptoms, hearing loss, and visual impairment. An important fact is that the typical triad of SuS symptoms in most cases does not occur simultaneously, which makes the diagnostic process very difficult and may lead to misdiagnosis.
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审稿时长
15 weeks
期刊介绍: The quarterly Current Problems of Psychiatry is a continuation of the volume "Research on Schizophrenia" and is addressed to a wide group of psychiatrists and clinical psychologists. The quarterly is a reviewed scientific journal of international scope, publishing original papers, review papers, case studies, conference reports, letters to the editor and book reviews. The aim of the "Current Problems of Psychiatry" is providing a wide audience with scientific works, representing a significant contribution to the development of psychiatry and clinical psychology. The works published in the journal are printed in Polish and English. Terms and Conditions for publishing manuscripts in the quarterly are available on the website www.cppsych.umlub.pl in the tab "Requirements".
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