Vikas Arora, Vishal Yadav, Manisha Aggarwal, Ghanashyam Mandal, Arnab Chakraborty, A K Dewan, Meenakshi Kamboj
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Collision Tumour of Combined Neuroendocrine and Squamous Cell Carcinoma of Nasal Cavity and Paranasal Sinus- Case Report and Review of Literature.
Background: There have been many disputes about the definition, diagnosis, therapy, and prognosis of collision tumours.
Case summary: We describe a rare patient with a collision tumour consisting of high-grade neuroendocrine carcinoma (NEC) and squamous cell carcinoma (SCC) in the right nasal cavity and paranasal sinus. She received surgery, concurrent chemoradiotherapy, and then two cycles of palliative chemotherapy. Follow-up at 26 months after diagnosis showed that this patient experienced a complete response with no signs of recurrence or metastasis. A literature review of previous 27 cases diagnosed with collision tumour of NEC and SCC in the head and neck was also undertaken.
Conclusion: It is highly challenging to manage collision tumours because these are two morphologically and etiologically distinct tumours. Well-designed multimodality therapy including surgery and chemoradiotherapy might lead to a long survival in these patients.
湖泊科学Environmental Science-Water Science and Technology
CiteScore
3.70
自引率
0.00%
发文量
3253
期刊介绍:
Journal of Lake Sciences (ISSN 1003-5427) was founded in 1989 and is jointly sponsored by Nanjing Institute of Geography and Lake Sciences, Chinese Academy of Sciences and Chinese Society of Oceanology and Limnology. It mainly reports the latest research results on the changes in resources, ecology and environment of lakes (including reservoirs) and their basins under the interaction between man and nature. It publishes theoretical or applied research papers, briefs and reviews on various disciplines related to lake science (such as physics, chemistry, biology, ecology, geology, geography, etc.) as well as lake engineering and integrated basin management. Since 2006, the journal has been changed to a bimonthly publication, published on January, March, May, July, September and November 6 by Science Press.