集成460纳米发光二极管的高分辨率神经深度探针，用于光遗传学应用

2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS) Pub Date : 2015-06-21 DOI:10.1109/TRANSDUCERS.2015.7181290

M. Schwaerzle, F. Pothof, Oliver Paul, P. Ruther

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引用次数: 16

摘要

我们报道了一种集成光源的聚合物基光极的设计、组装、光学和热特性，用于光遗传学。这种新型探针可以光学刺激大脑深层区域的神经脑组织，并同时使用集成的大电极和微电极记录大脑活动。光极是基于一个圆柱形的聚酰亚胺(PI)探针，它携带电极和它们各自的线路。一个裸露的发光二极管(LED)芯片集成在这个圆柱体内，并通过一个单独的基于pi的带状电缆进行电气连接。

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High-resolution neural depth probe with integrated 460 NM light emitting diode for optogenetic applications

We report on the design, assembly, and optical as well as thermal characterization of a polymer-based optrode with an integrated light source for applications in optogenetics. The novel probe allows to optically stimulate neural brain tissue in deeper brain regions and to simultaneously record brain activity using integrated macroelectrodes and microelectrodes. The optrode is based on a cylindrical polyimide (PI) probe carrying the electrodes and their respective wiring. A bare light emitting diode (LED) chip is integrated within this cylinder and electrically interconnected through a separate PI-based ribbon cable.

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2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)

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