聚乙烯氧化物左乙拉西坦基质片的制备及评价

Y. Raut, A. Dubey
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引用次数: 1

摘要

请引用这篇文章:Raut YB等人,聚乙烯氧化物制备左乙拉西坦基质片剂及其评价。美国医药技术研究杂志2019。李建平,李建平,李建平,等。聚乙烯氧化物制备左乙拉西坦基质片剂的研究进展[j]。2.马哈拉施特拉邦布尔达纳区萨哈克赫尔达-443201,加万德药学院药剂学系;摘要以聚乙烯氧化物(PEO 301、PEO混凝剂和PEO 303)为原料,以不同浓度的PEO 301、PEO混凝剂和PEO 303为原料,采用湿造粒技术制备左乙莱西坦基质片剂,并对其进行表征。采用差示扫描量热法(DSC)、傅里叶变换红外光谱(FTIR)对优化后的配方进行了评价。结果表明,与PEO 303 (T10)联合制备的左乙拉西坦的控释时间在12 h以上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Formulation and Evaluation of Levetiracetam Matrix Tablet Using Polyethylene Oxides
Please cite this article as: Raut YB et al., Formulation and Evaluation of Levetiracetam Matrix Tablet Using Polyethylene Oxides. American Journal of PharmTech Research 2019. Formulation and Evaluation of Levetiracetam Matrix Tablet Using Polyethylene Oxides Y.B Raut*, A.S. Dubey 1.Department of Pharmaceutics, Gawande College of pharmacy, Sakharkherda-443201, Dist. Buldana, Maharashtra 2.Department of Pharmaceutics, CSM University, Kanpur, U.P ABSTRACT The objective of work was to prepare and characterize Levetiracetam matrix tablet using Polyethylene oxides (PEO 301, PEO coagulant and PEO 303) by wet granulation technique using variable concentrations of PEO 301, PEO coagulant and PEO 303. Total 12 formulations were prepared and optimized formulation were evaluated by Differential scanning Calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) and The results obtained showed that the formulations of Levetiracetam prepared with combination PEO 303 (T10) has controlled release over 12 hrs.
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