特异性靶向抗菌肽的选择性抗菌治疗新途径

Bharati Das, Maneesh Jain
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引用次数: 0

摘要

摘要-尽管口腔微生物组是身体上最复杂的部位之一,但它是细长范围抗菌治疗的杰出模型。潮起潮落的研究表明,考虑到致病物种的丰度和口腔疾病的开始,微生物组的中断会引发一个生态失调域。一段时间以来,革兰氏阴性定植菌牙龈卟啉单胞菌被认为是牙周炎开始的关键因素,变形链球菌被认为与龋齿有关。随着抗毒素检查仍在减少,新的方法令人难以置信地有望与不可抗拒的疾病作斗争。通过关注关键病原体,可以想象在治疗口腔感染的同时考虑到有益的、健康的青苔的重新定植。在这个重新看到,我们看看一种程序明确针对牙周病原体和解决什么是需要完成这些方法在微生物组时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A New and Promising Avenue In Selective Antimicrobial Treatment For Particularly Targeted Antimicrobial Peptides
Abstratct – Despite the fact that the oral microbiome is a standout amongst the most complex locales on the body it is a brilliant model for slender range antimicrobial treatment. Ebb and flow investigate demonstrates that interruption of the microbiome prompts a dysbiotic domain taking into consideration the abundance of pathogenic species and the beginning of oral maladies. The gram-negative colonizer, Porphyromonas gingivalis has for some time been viewed as a key player in the initiation of periodontitis and Streptococcus mutans has been connected to dental caries. With anti-toxin examine still on the decrease, new methodologies are incredibly expected to battle irresistible sicknesses. By focusing on key pathogens, it might be conceivable to treat oral infections while taking into account the recolonization of the gainful, sound verdure. In this re-see, we look at one of a kind procedure to explicitly target periodontal pathogens and address what is required for the accomplishment of these methodologies in the microbiome time.
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