胶原膜修复口腔黏膜下纤维化黏膜缺损的疗效评价

Manasi Dutt, Sourav Kumar, Dipti D. Nayak, Musaab Khan, Shashanka P. Kumar, Neha Nayak
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引用次数: 0

摘要

背景:口腔黏膜下纤维化是一种很好的癌前病变。通过本文,试图提高外科治疗的知识,以提高OSMF患者的生存预期。材料与方法:本研究纳入15例年龄在15 ~ 60岁的口腔黏膜下纤维化II、III、IVa期患者,均由同一术者在全身麻醉下切除纤维带,置入胶原膜,以增加口腔开口。术后,所有患者均给予类似的镇痛药、抗生素处方和术后指导。所有患者于术后第1周、第2周、第3周至第6个月复查。结果:本组OSMF的平均发病年龄为2 ~ 3岁,男性多见(86.6%)。所有患者术前口开度平均值为16.4 mm。术后1周平均口开度为24.96 mm,术后2个月在严格的物理治疗下逐渐增加至28.16 mm。随访6个月,平均开口连续月略有增加,为29.1 mm。结论:在我们的研究中,我们注意到手术切除纤维带和放置胶原膜提供了令人满意的结果,直到最后一个随访月,患者的开口与术前相比有明显的增加。然而,为了证明一个更显著的结果,我们需要更大的样本量,以及更长的随访时间来建立同样的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the efficacy of collagen membrane for mucousal defect in oral sub mucous fibrosis
Background: Oral submucous fibrosis is well diagnosed as a premalignant condition. Through this article, an attempt was tried to improve the knowledge regarding surgical management which improves the existence expectancy of patients suffering from OSMF. Materials and Methods: The study included 15 patients in the age group of 15 to 60 years with stage II, III and IVa of oral submucous fibrosis all of which underwent operation under general anesthesia to facilitate an increase in their mouth opening by excision of fibrous bands and placement of collagen membrane by the same operator. After surgery, all were given similar prescriptions for analgesics, antibiotics, and postoperative instructions. All patients were reviewed at 1st week, 2nd week, 3rd week till 6th months postoperatively. Results: In this study, the mean age of occurrence of OSMF was 2nd to 3rd decade of life with males (86.6%) more commonly affected. The preoperative mouth opening was a mean value of 16.4 mm in all patients. At the first week postoperatively, a mean mouth opening of 24.96 mm was achieved which gradually increased to a mean mouth opening of 28.16 mm at the 2nd month with the help of rigorous physiotherapy. There was a slight gradual increase of mean mouth opening at consecutive months at 29.1 mm at the follow-up period of 6th months. Conclusion: In our study, we noticed that surgical excision of fibrous bands and placement of collagen membrane provided us with satisfactory results, there was a significant increase in the mouth opening of the patients till the last follow-up month as compared to the preoperative mouth opening. However, to prove a more significant result, we need a larger sample size, as well as a longer follow-up for the establishment of the same.
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