青光眼周期危机-一种难以捉摸的疾病:我们的管理经验和结果

S. Parvez, S. Noman
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引用次数: 0

摘要

背景:本研究的目的是描述在吉大港眼科医院和培训中心(CEITC)青光眼科和吉大港医学院眼科诊断为青光眼周期危象的患者的临床表现、处理和结局。材料和方法:以医院为基础的观察性病例系列研究。研究时间为2010年7月1日至2012年6月30日。本研究纳入吉大港医学院附属医院门诊部及吉大港医学院附属医院眼科青光眼门诊就诊的不明原因单侧高眼压病例。详细的病史和眼部检查包括针灯生物显微镜、压血压计、眼膜镜、眼底镜和视野分析。根据上述标准诊断为青光眼循环危象(GCC)。记录管理细节。患者分别于1个月、1个月、3个月初访后随访。尽可能多地记录检查和调查结果。样本量为45。结果:共纳入45例GCC患者。为了更好地了解结果,将45例患者分为20-49岁和50岁以上2个年龄组。两组患者的比例分别为51.1% (n=23)和48.9% (n=22)。共45例,其中男37例,女8例。53.3% (n=24)的患者表现为视力下降,15.6% (n=7)的患者同时伴有疼痛和偶发红肿,13.3% (n=6)的患者表现为轻度不适,11.1% (n=5)的患者表现为复发性红肿,8.9% (n=4)的患者表现为偶发光晕,4.4% (n=2)的患者表现为偶发眼痛,2.2% (n=1)的患者表现为视力丧失。治疗前患眼平均IOP为30mm hg,治疗后平均IOP为15mm hg。所有病例的角度都是开放的。81.2%的患者(n-37)就诊时表现为青光眼视盘C:D比值(0.8-1):1。77.77% (n=35)的患者需要氟美酮,4.44% (n=2)的患者需要地塞米松,4.44% (n=2)的患者需要醋酸泼尼松龙滴眼液来控制炎症。13.33%的患者(n=6)未使用任何类固醇治疗,因为它们自行消退。91%的患者需要抗青光眼药物治疗,9%的患者需要滤过手术加ogen植入术来控制IOP。结论:早期诊断,仔细检查和调查是处理GCC病例的必要条件。由于这是一种难以捉摸的疾病,因此对患者进行适当的解释,使患者有良好的依从性,才能达到良好的医疗效果。良好的滤过手术配合ogen植入术仍能成功控制IOP。但定期对患者进行仔细监测是必要的,以完美地管理和防止疾病复发的不可逆转的视觉后果。Jcmcta 2020;31 (1): 81-85
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Glaucomatocyclitic Crisis - An Elusive Disease: Our Experience in Management and Outcomes
Background: The purpose of the current study is to describe clinical manifestations, management and its outcome of patients who were diagnosed as glaucomatocyclitic crisis at the Glaucoma Department Chittagong Eye Infirmary and Training Complex (CEITC) Chattogram and Eye Department, Chittagong Medical College. Materials and methods: It is a hospital based observational case series study. Study period was from 1st July 2010-to 30th June 2012.Unilateral ocular hypertension cases of unexplained origin referred to glaucoma clinic from outpatient department of CEITC and Eye Department, Chittagong Medical College Hospital (CMCH) were included in this study. Detail history taking and ocular examinations were done that included stitlamp biomicroscopy, applanation tonometry, gonioscopy, fundoscopy and visual field analysis. Glaucomatocyclitic Crisis (GCC) was diagnosed according to mentioned criteria. Management detail was recorded. Patients were followed up after one weak, 1 month, 3 months of initial visit. Examination and investigation findings were documented as much as possible. Sample size was 45. Results: A total numbers of 45 patients with GCC were included. For the better understanding the results, the total patients (N=45) were categorized into 2 age groups that are 20-49 and 50+. Percentage of patients into these groups are 51.1% (n=23) and 48.9% (n=22) respectively. In total 45 patients, 37 were male and 8 were female. 53.3% patients (n=24) presented with decreased visions, 15.6% patients (n=7) with both pain and occasional redness, 13.3% patients (n=6) with mild discomfort, 11.1% patients (n=5) with recurrent redness, 8.9% patients (n=4) with occasional halos, 4.4% patients (n=2) with occasional eye ache and 2.2% patient (n=1) with loss of vision. Mean IOP of affected eyes was 30mm hg before treatment and 15mm hg after treatment. Angles were open in all cases.  At presentation 81.2% patients (n-37) presented with glaucomatous optic disc C:D ratio (0.8-1):1. 77.77% patients(n=35) needed flurometholone, 4.44% cases (n=2) needed dexamethasone and 4.44% patients (n=2) needed prednisolone acetate topical eye drop to control inflammation. 13.33% patients (n=6) were not treated with any steroid as they resolved spontaneously. 91% patients needed anti glaucoma medications 9% needed filtration surgery with Ologen implantation to control IOP.   Conclusion: Early diagnosis with meticulous examinations and investigations are needed to manage a GCC case. As it is an elusive disease, proper explanation of the disorder to the patient to get good compliance from them is necessary to achieve good medical treatment outcome. Good filtration surgery with Ologen implantation is still successful to control IOP. But regular careful monitoring to the patient is mandatory to perfectly manage and prevent the irreversible visual consequences of recurrence of the disease. JCMCTA 2020 ; 31 (1) : 81-85
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