使用回放转换的核苷酸变形

B. Kathiresan, G. Karthik
{"title":"使用回放转换的核苷酸变形","authors":"B. Kathiresan, G. Karthik","doi":"10.1109/ICCCNT.2013.6726612","DOIUrl":null,"url":null,"abstract":"Bioinformatics is the application of computer technology for the management and analysis of biological data. Pattern matching in a DNA sequence or searching a pattern from a large data base is a major research area in computational biology. One of the major problems in genomic field is to perform pattern comparison on DNA and protein sequences. A full DNA strand contains three billion of nucleotide bases. To parse and to convert amino acids of high volume, the existing approach takes some minutes. If the conversion process is aborted in middle, it will restart from the beginning again. In order to overcome this drawback, the playback conversion approach is proposed to continue the process from where it aborted. And the subsequent implementation of this approach in parallel mode will reduce forty percent of time taken by the existing approach. This paper entirely focuses on an approach to reduce the time taken for the conversion of nucleotide to amino acids. The proposed technique gives very good performance related to DNA sequence analysis for querying of publicly available genome sequence data. These experimental results show that there is considerable increase in the improvement of overall performance.","PeriodicalId":6330,"journal":{"name":"2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2013-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nucleotide transfigurations using playback conversion\",\"authors\":\"B. Kathiresan, G. Karthik\",\"doi\":\"10.1109/ICCCNT.2013.6726612\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bioinformatics is the application of computer technology for the management and analysis of biological data. Pattern matching in a DNA sequence or searching a pattern from a large data base is a major research area in computational biology. One of the major problems in genomic field is to perform pattern comparison on DNA and protein sequences. A full DNA strand contains three billion of nucleotide bases. To parse and to convert amino acids of high volume, the existing approach takes some minutes. If the conversion process is aborted in middle, it will restart from the beginning again. In order to overcome this drawback, the playback conversion approach is proposed to continue the process from where it aborted. And the subsequent implementation of this approach in parallel mode will reduce forty percent of time taken by the existing approach. This paper entirely focuses on an approach to reduce the time taken for the conversion of nucleotide to amino acids. The proposed technique gives very good performance related to DNA sequence analysis for querying of publicly available genome sequence data. These experimental results show that there is considerable increase in the improvement of overall performance.\",\"PeriodicalId\":6330,\"journal\":{\"name\":\"2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-07-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICCCNT.2013.6726612\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICCCNT.2013.6726612","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

生物信息学是应用计算机技术对生物数据进行管理和分析的学科。DNA序列的模式匹配或从大型数据库中搜索模式是计算生物学的一个主要研究领域。基因组学领域的主要问题之一是如何对DNA和蛋白质序列进行模式比较。一条完整的DNA链包含30亿个核苷酸碱基。为了解析和转换大量的氨基酸,现有的方法需要几分钟。如果转换过程中途中止,它将重新开始。为了克服这个缺点,建议使用重放转换方法从中断的地方继续进程。并且该方法在并行模式下的后续实现将减少现有方法所花费的时间的40%。这篇论文完全集中在一种方法,以减少所需的时间为核苷酸转化为氨基酸。该技术在DNA序列分析方面具有很好的性能,可用于查询公开可用的基因组序列数据。这些实验结果表明,在整体性能的提高上有相当大的提高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nucleotide transfigurations using playback conversion
Bioinformatics is the application of computer technology for the management and analysis of biological data. Pattern matching in a DNA sequence or searching a pattern from a large data base is a major research area in computational biology. One of the major problems in genomic field is to perform pattern comparison on DNA and protein sequences. A full DNA strand contains three billion of nucleotide bases. To parse and to convert amino acids of high volume, the existing approach takes some minutes. If the conversion process is aborted in middle, it will restart from the beginning again. In order to overcome this drawback, the playback conversion approach is proposed to continue the process from where it aborted. And the subsequent implementation of this approach in parallel mode will reduce forty percent of time taken by the existing approach. This paper entirely focuses on an approach to reduce the time taken for the conversion of nucleotide to amino acids. The proposed technique gives very good performance related to DNA sequence analysis for querying of publicly available genome sequence data. These experimental results show that there is considerable increase in the improvement of overall performance.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信