H3K9me2和E-cadherin的表达与宫颈癌侵袭性的关系

Journal of oncology research and therapy Pub Date : 2023-08-07 DOI:10.29011/2574-710x.10179

Ruey-Jien Chen, Chia-Hung Chou, Chia-Tung Shun, Wen-Fen Wen, Men-Luh Yen, Shee-Uan Chen

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摘要

目的:探讨H3K9me2基因是否与宫颈癌侵袭性有关。方法:共纳入480例宫颈癌组织阵列样本和55例匹配的宫颈癌患者。免疫组化染色检测E-cadherin、SIRT1、ZEB-1、MPP8蛋白表达，qRT-PCR检测mRNA表达

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Expressions of H3K9me2 and E-cadherin Correlate with Cervical Cancer Invasiveness

Objective: To investigate whether H3K9me2 is linked to cervical cancer invasiveness. Methods: A total of 480 cervical cancer tissue array samples and 55 matched cervical cancer patients were enrolled. Immunohistochemical staining was used to analyze E-cadherin, SIRT1, ZEB-1, MPP8 protein expression, while qRT-PCR was used to estimate mRNA

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Journal of oncology research and therapy

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