患者依赖参数与使用18f - fdg进行PET/CT成像患者周围测量的辐射剂量率的关系

K. Soliman, S. Qahtani, A. Alenezi
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摘要

目的:接受18F-FDG PET/CT成像的患者被认为是外部辐射源。准确的剂量率估计对于进行现实的风险评估和在意外照射情况下进行剂量重建非常重要。假设患者辐射自衰减因子是患者体型指标的函数,但我们可以利用这些指标准确地预测患者周围的剂量率。这项工作的目的是首先通过对使用18F-FDG进行PET/CT成像研究的患者进行直接剂量率测量来测量患者的衰减因子。第二个目标是研究从患者身上测量到的每单位活动剂量率常数与他们的体型指标之间可能存在的相关性;在这项工作中测试了五个指标。最后一个目的是测量患者的排尿因子。方法:我们测量了57例患者一米处的剂量率,记录了患者的身高(H)、体重(W),并计算了患者的尺寸指标,即等效圆柱直径(ECD)、等效球面直径(ESD)和身体质量指数(BMI)。结果:测得的平均剂量率为92.2±14 μSv·h-1·GBq-1。因此,AAPM, TG-108报告提出的92 μSv·h-1·GBq-1的剂量率常数可以满足辐射防护要求。单位活动剂量率常数与患者体型指标之间没有统计学上的显著相关性。我们测量的患者排尿因子为0.89±0.06,而AAPM推荐的为0.85。结论:本研究数据可用于核医学领域的医学物理学家对接受18F-FDG PET/CT成像的患者的辐射暴露进行更准确的风险评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between Patient-Dependent Parameters and Radiation Dose Rates Measured around Patients Undergoing PET/CT Imaging Using 18 F-FDG
Objectives: Patients undergoing 18F-FDG PET/CT imaging are considered external radiation sources. Accurate dose rate estimates are important for conducting realistic risk assessments and performing dose reconstruction in cases of accidental exposures. The patient radiation self-attenuation factor is assumed to be a function of the patient’s body size metrics, but we can use these metrics to predict the dose rate around the patients with accuracy. The objective of this work was first to measure the patient attenuation factor by performing direct dose rate measurements from patients undergoing PET/CT imaging studies using 18F-FDG. The second objective was to study the possible correlation between the measured dose rate constant per unit activity from the patients and their body size metrics; five metrics were tested in this work. The last objective was to measure the patients’ voiding factor. Methods: We have measured dose rates at one meter from 57 patients and noted the patient’s height (H), weight (W) and calculated patient size metrics namely: Equivalent Cylindrical Diameter (ECD), Equivalent Spherical Diameter (ESD) and the Body Mass Index (BMI). Results: The measured average dose rate was 92.2 ± 14 μSv·h-1·GBq-1 measured at one meter. Therefore, the dose rate constant of 92 μSv·h-1·GBq-1 proposed by the AAPM, TG-108 report is adequate for radiation protection purposes. There was no statistically significant correlation between the dose rate constant per unit activity and the patient body size metrics. We have measured a patient voiding factor of 0.89 ± 0.06 in comparison with 0.85 recommended by the AAPM. Conclusions: The presented data can be used by medical physicist working in nuclear medicine in formulating more accurate risk estimations resulting from radiation exposure from patients undergoing 18F-FDG PET/CT imaging.
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