Iury Matheus Lima Cavalcanti, Cristian Rodrigues do Nascimento, P. P. Tenório, T. Araújo
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引用次数: 0
摘要
背景:肥胖是一个公共卫生问题,与代谢紊乱的发展有关,代谢紊乱与心血管疾病(CVD)的发病有很强的关系。目的:目的是分析腹部肥胖(AO)对成年女性全身性动脉高血压(SAH)和心血管危险分层中脂质谱的影响。方法:共有91名女性参与了研究。收集生活方式信息,分析心血管风险的临床指标和生化参数。数据分析采用Unpaired Student t检验、logistic回归和Pearson相关分析,p <0.05为显著性。结果:AO患病率为62.6%。Logistic回归显示,AO使SAH发生的几率增加了2.9倍。在TG/HDL-c脂质比率(3.93±0.3 vs. 2.16±0.2)中观察到同样的行为,肥胖女性增加了82%。本研究还表明,分析研究人群心血管风险的最佳人体测量参数是腰高比(AUC = 0.707)。结论:因此可以得出结论,AO在SAH的发展和预测心血管风险增加的脂质值变化中起着重要作用,是CVD的一个重要影响因素。
Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women
Background: Obesity is a public health problem and has been associated with the development of metabolic disorders that have a strong relationship with the onset of cardiovascular diseases (CVD). Objective: The objective was to analyze the influence of abdominal obesity (AO) on systemic arterial hypertension (SAH) and on the lipid profile in cardiovascular risk stratification in adult women. Methods: Altogether, 91 women participated in the research. Lifestyle information was collected, in addition to the analysis of clinical measures of cardiovascular risk and biochemical parameters. Unpaired Student's t-test, logistic regression, and Pearson's correlation were performed for data analysis, with a value of p <0.05 considered significant. Results: The prevalence of AO was 62.6%. Logistic regression showed that AO increased the chance of developing SAH by 2.9-fold. The same behavior was observed in the TG/HDL-c lipid ratio (3.93 ± 0.3 vs. 2.16 ± 0.2), representing an 82% increase in obese women. The present study also demonstrated that the best anthropometric parameter to analyze cardiovascular risk in the studied population was the waist/height ratio (AUC = 0.707). Conclusions: It can therefore be concluded that AO plays a significant role in the development of SAH and changes in lipid values that predict increased cardiovascular risk, configuring a strong influence factor for CVD.