各种水溶性C60衍生物的合成及其超氧猝灭活性

Fullerene Science and Technology Pub Date : 2000-01-01 DOI:10.1080/10641220009351400

K. Okuda, T. Hirota, M. Hirobe, T. Nagano, M. Mochizuki, T. Mashino

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引用次数: 36

摘要

摘要为了研究富勒烯的药用价值，我们在体外研究了富勒烯衍生物与活性氧的反应。本文介绍了各种水溶性C60衍生物(阳离子和阴离子)的合成及其超氧化物(O2−)猝灭活性的评价。阳离子C60衍生物表现出相当高的效率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Synthesis of Various Water-Soluble C60 Derivatives and Their Superoxide-Quenching Activity

Abstract In order to examine the utility of fullerene as a medicinal application, we evaluated the reaction between fullerene derivatives and active oxygen species in vitro. This paper describes the synthesis of various water-soluble C60 derivatives (cationic and anionic) and evaluation of their superoxide (O2 −) quenching activity. Cationic C60 derivatives showed fairly high efficiency.

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Fullerene Science and Technology

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