三波长和810纳米二极管激光脱毛:在印度皮肤的临床和硅比较研究

A. Pall, Gregorio Viera-Mármol
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引用次数: 0

摘要

在对深色皮肤进行激光脱毛治疗时,皮肤中的高浓度黑色素与头发中的黑色素相互竞争。在标准激光过程中,波长为755 nm或810 nm,观察到皮肤中的黑色素对激光的高水平吸收。因此,为了避免副作用,使用较低的影响值,这进一步降低了脱毛效果。为了改善结果,通常使用在动态模式下工作的810 nm二极管激光器,具有高频率和多通道。本研究的目的是比较三波长二极管激光器(810 nm, 940 nm, 1060 nm)与810 nm二极管激光器对印度患者的疗效和安全性。用三波长二极管激光器在冲压模式下与810 nm二极管激光器在动态模式下进行并排比较。三名Fitzpatrick皮肤类型为IV型的受试者参与了这项研究。通过毛发计数、治疗前后拍摄的临床照片和全球审美改善量表(GAIS)来评估疗效。此外,使用COMSOL Multiphysics®软件通过数学3D模拟进行了与表皮加热和毛囊热损伤相关的比较。对副作用也进行了评估。与810 nm二极管激光器相比,在三波长处观察到更好的终点。头发计数显示多了27%
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Triple Wavelength and 810 nm Diode Lasers for Hair Removal: A Clinical and in Silico Comparative Study on Indian Skin
In laser hair removal treatments on dark skin, the high concentration of melanin in the skin competes with the melanin in the hair. During standard laser procedures, with wavelengths of 755 nm or 810 nm, a high level of laser light absorption by melanin in the skin is observed. Therefore, to avoid side effects, lower fluence values are used, which further reduces hair-removal efficacy. To improve results, 810 nm diode lasers operating in dynamic mode, with high frequency and multiple passes, are typically used. The aim of this study is to compare the efficacy and safety of triple-wavelength diode lasers (810 nm, 940 nm, 1060 nm) with that of 810 nm diode lasers on Indian patients. A side-by-side comparison was performed using a triple-wavelength diode laser in stamping mode on one side, and an 810 nm diode laser in dynamic mode on the other. Three subjects with skin type IV on the Fitzpatrick scale participated in the study. Efficacy was assessed through hair counting using clinical photographs, taken before and after the treatments, and the Global Aes-thetic Improvement Scale (GAIS). Additionally, comparisons related to epidermal heating and thermal damage to the hair follicle were conducted through mathematical 3D simulations using COMSOL Multiphysics ® software. Side effects were also evaluated. A superior end point was observed with triple wavelength compared to the 810 nm diode laser. Hair counting showed a 27% greater hair
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