Total body exposure to ultraviolet radiation does not influence plasma levels of immunoreactive beta-endorphin in man.

UVA-1. Plasma ACTH-IR was monitored in parallel. Results: Overall, plasma levels of bE-IR and ACTHIR showed no significant changes during the experiment, indicating that these peptides are not influenced by single or repeated exposures to UVR of different wavelengths. Conclusion: On the basis of these results, the skin does not appear to contribute significantly to the levels of circulating bE or ACTH. These data offer no support for the hypothesis that exposure to UVR leads to an increased concentration of circulating bE, which could contribute to the feeling of well-being that often accompanies sun-bathing.