抗COVID-19的药用植物天然化合物

A. Kolodnitsky, N. Ionov, I. Gravel, V. Poroikov
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引用次数: 0

摘要

已知导致2019冠状病毒病(COVID-19)的严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)于2020年初被宣布为大流行。在过去的一段时间里,已经开发了几种感染控制方法。然而,它们都有一定的局限性:持续时间的不确定性、疫苗的效力有限、缺乏有效的COVID-19治疗药物。因此,为对症和致病因治疗创造药物的问题仍然是相关的。本文通过分析体外研究和已完成的临床试验(CTs)的结果,总结了目前使用天然化合物作为抗sars - cov -2药物的知识。此外,本工作突出了最具活性的分子,并讨论了在临床实践中使用某些化合物的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Natural compounds from medicinal plants against COVID-19
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the past time, several infections control methods have been developed. Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. So, the issue of creating drugs for symptomatic and etiotropic therapy is still relevant. This review summarizes the current knowledge of using natural compounds as anti-SARS-CoV-2 agents by analysing the results of in vitro studies and completed clinical trials (CTs). Also, this work highlighted the most active molecules and discussed the possibility of using some compounds in clinical practice.
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