诊断测试在个体化医疗中的价值

Q3 Economics, Econometrics and Finance

Forum for Health Economics and Policy Pub Date : 2013-09-01 DOI:10.1515/fhep-2013-0023

D. Goldman, Charu N. Gupta, E. Vasudeva, K. Trakas, R. Riley, D. Lakdawalla, D. Agus, N. Sood, A. Jena, T. Philipson

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引用次数: 21

摘要

个性化医疗——根据个体的生物学、临床或遗传特征对其进行靶向治疗——被认为具有改变医疗保健的潜力。虽然很多人强调个性化治疗的价值，但很少有人关注引导患者接受这些针对性治疗的诊断测试所产生的价值。本文提出了一个源自信息经济学的框架，用于评估诊断的价值。我们通过一个案例研究证明，这种诊断的社会价值可以非常大，既可以避免不必要的治疗，也可以识别出本来不会得到治疗的患者。尽管有潜在的社会效益，但基于成本而不是基于价值的报销阻碍了诊断的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Value of Diagnostic Testing in Personalized Medicine

Abstract Personalized medicine – the targeting of therapies to individuals on the basis of their biological, clinical, or genetic characteristics – is thought to have the potential to transform health care. While much emphasis has been placed on the value of personalized therapies, less attention has been paid to the value generated by the diagnostic tests that direct patients to those targeted treatments. This paper presents a framework derived from information economics for assessing the value of diagnostics. We demonstrate, via a case study, that the social value of such diagnostics can be very large, both by avoiding unnecessary treatment and by identifying patients who otherwise would not get treated. Despite the potential social benefits, diagnostic development has been discouraged by cost-based, rather than value-based, reimbursement.

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来源期刊

Forum for Health Economics and Policy Economics, Econometrics and Finance-Economics, Econometrics and Finance (miscellaneous)

CiteScore

1.60

自引率

0.00%

发文量

期刊介绍： Forum for Health Economics & Policy (FHEP) showcases articles in key substantive areas that lie at the intersection of health economics and health policy. The journal uses an innovative structure of forums to promote discourse on the most pressing and timely subjects in health economics and health policy, such as biomedical research and the economy, and aging and medical care costs. Forums are chosen by the Editorial Board to reflect topics where additional research is needed by economists and where the field is advancing rapidly. The journal is edited by Katherine Baicker, David Cutler and Alan Garber of Harvard University, Jay Bhattacharya of Stanford University, Dana Goldman of the University of Southern California and RAND Corporation, Neeraj Sood of the University of Southern California, Anup Malani and Tomas Philipson of University of Chicago, Pinar Karaca Mandic of the　University of Minnesota, and John Romley of the University of Southern California. FHEP is sponsored by the Schaeffer Center for Health Policy and Economics at the University of Southern California. A subscription to the journal also includes the proceedings from the National Bureau of Economic Research''s annual Frontiers in Health Policy Research Conference. Topics: Economics, Political economics, Biomedical research and the economy, Aging and medical care costs, Nursing, Cancer studies, Medical treatment, Others related.