肿瘤筛查关键参数估算及预估时间研究进展

Q3 Mathematics

Revista Colombiana De Estadistica Pub Date : 2017-07-01 DOI:10.15446/RCE.V40N2.60642

Ruiqi Liu, J. Gaskins, Riten Mitra, Dongfeng Wu

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引用次数: 3

摘要

早期发现和有效治疗是对抗癌症的唯一途径，而癌症筛查是早期发现的主要技术。虽然大规模的癌症筛查已经开展了几十年，但仍有许多未解决的问题，癌症筛查的统计理论仍处于发展阶段。筛查敏感性、临床前状态持续时间和无病状态持续时间是癌症筛查中至关重要的三个关键参数，因为所有其他估计都是这三个关键参数的函数。提前期是通过筛查提前的诊断时间，它是筛查方案有效性的衡量标准。在这篇文章中，我们提供了一个主要的概率模型和统计方法，已经开发的估计三个关键参数和提前期分布。这些方法稍加修改后，可应用于其他慢性病的筛查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Review of Estimation of Key Parameters and Lead Time in Cancer Screening

Early detection combined with effective treatments are the only ways to fight against cancer, and cancer screening is the primary technique for early detection. Although mass cancer screening has been carried out for decades, there are many unsolved problems, and the statistical theory of cancer screening is still under developed. Screening sensitivity, time duration in the preclinical state, and time duration in the disease free state are the three key parameters, which are critical in cancer screening, since all other estimates are functions of the three key parameters. Lead time is the diagnosis time advanced by screening, and it serves as a measurement of effectiveness of screening programs. In this article, we provide a review for major probability models and statistical methodologies that have been developed on the estimation of the three key parameters and the lead time distributions. These methods can be applied to screening of other chronic diseases after slight modifications.

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来源期刊

Revista Colombiana De Estadistica STATISTICS & PROBABILITY-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Colombian Journal of Statistics publishes original articles of theoretical, methodological and educational kind in any branch of Statistics. Purely theoretical papers should include illustration of the techniques presented with real data or at least simulation experiments in order to verify the usefulness of the contents presented. Informative articles of high quality methodologies or statistical techniques applied in different fields of knowledge are also considered. Only articles in English language are considered for publication. The Editorial Committee assumes that the works submitted for evaluation have not been previously published and are not being given simultaneously for publication elsewhere, and will not be without prior consent of the Committee, unless, as a result of the assessment, decides not publish in the journal. It is further assumed that when the authors deliver a document for publication in the Colombian Journal of Statistics, they know the above conditions and agree with them.