蓝藻毒素的神经毒性

M. Florczyk, A. Łakomiak, M. Woźny, P. Brzuzan
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引用次数: 24

摘要

海水和淡水的富营养化可能导致蓝藻过度繁殖,其中可能含有产生毒素的菌株。这些毒素是次生代谢物,可在食物链中积累并污染饮用水,从而对人类和水生生物的健康构成潜在威胁。这些毒素包括各种具有不同机制的化合物。本文综述了微囊藻毒素和其他蓝藻毒素的神经毒性。虽然微囊藻毒素的肝毒性作用是众所周知的,但其神经毒性作用也已被描述,例如氧化应激,细胞骨架变化和
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurotoxicity of cyanobacterial toxins
Eutrophication of marine- and fresh-waters can lead to excessive development of cyanobacterial blooms, which may contain strains that produce toxins. These toxins are secondary metabolites which can accumulate in the food chain and contaminate drinking water, thus posing a potential threat to the health of humans and aquatic organisms. These toxins include a variety of compounds with different mechanisms. This review focuses on the neurotoxicity of microcystin and other cyanotoxins. Although the hepatotoxic action of microcystins is commonly known, its neurotoxic effects have also been described, e.g. oxidative stress, cytoskeletal changes and
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